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10.4103/JMAU.JMAU_63_20

http://scihub22266oqcxt.onion/10.4103/JMAU.JMAU_63_20
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33623736!7883493!33623736
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suck abstract from ncbi


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pmid33623736      J+Microsc+Ultrastruct 2020 ; 8 (4): 141-145
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  • COVID-19 and Phosphodiesterase Enzyme Type 5 Inhibitors #MMPMID33623736
  • Al-Kuraishy HM; Al-Gareeb AI; Al-Niemi MS; Al-Buhadily AK; Al-Harchan NA; Lugnier C
  • J Microsc Ultrastruct 2020[Oct]; 8 (4): 141-145 PMID33623736show ga
  • COVID-19 pathology is mainly associated to a pulmonary disease which sometimes might result in an uncontrollable storm related to inflammatory diseases which could be fatal. It is well known that phosphodiesterase enzyme type 5 inhibitors (PDE5Is), such as sildenafil, have been successfully developed for the treatment of pulmonary arterial hypertension; interestingly, more recently, it was shown that PDE5Is might be also anti-inflammatory. Therefore, it would be of interest to question about the use of PDE5Is to overcome the COVID-19 storm, as much as PDE5 is mainly present in the lung tissues and vessels.
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