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10.1136/bcr-2020-241047

http://scihub22266oqcxt.onion/10.1136/bcr-2020-241047
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33622757!7907860!33622757
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suck abstract from ncbi

pmid33622757      BMJ+Case+Rep 2021 ; 14 (2): ä
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  • COVID-19 cardiac injury and the use of colchicine #MMPMID33622757
  • Anton-Vazquez V; Byrne L; Anderson L; Hamzah L
  • BMJ Case Rep 2021[Feb]; 14 (2): ä PMID33622757show ga
  • We report a case of cardiac injury in a 46-year-old man affected by COVID-19. The patient presented with shortness of breath and fever. ECG revealed sinus tachycardia with ventricular extrasystoles and T-wave inversion in anterior leads. Troponin T and N-terminal pro B-type natriuretic peptide were elevated. Transthoracic echocardiography showed severely reduced systolic function with an estimated left ventricle ejection fraction of 30%. A nasopharingeal swab was positive for SARS-CoV-2. On day 6, 11 days after onset of symptoms, the patient deteriorated clinically with new chest pain and type 1 respiratory failure. Treatment with colchicine 0.5 mg 8-hourly resulted in rapid clinical resolution. This case report highlights how cardiac injury can dominate the clinical picture in COVID-19 infection. The role of colchicine therapy should be further studied to determine its usefulness in reducing myocardial and possibly lung parenchymal inflammatory responses.
  • |*COVID-19 Drug Treatment[MESH]
  • |COVID-19/*complications[MESH]
  • |Chest Pain/virology[MESH]
  • |Colchicine/*therapeutic use[MESH]
  • |Echocardiography[MESH]
  • |Heart Diseases/*drug therapy/*virology[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Myocardium/pathology[MESH]
  • |Natriuretic Peptide, Brain/blood[MESH]
  • |Peptide Fragments/blood[MESH]
  • |Systole[MESH]


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