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10.6002/ect.2020.0296

http://scihub22266oqcxt.onion/10.6002/ect.2020.0296
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33622217!ä!33622217

suck abstract from ncbi


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pmid33622217      Exp+Clin+Transplant 2022 ; 20 (11): 980-983
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  • Mesenchymal Stem Cell-Derived Extracellular Vesicles: Promising Treatment for COVID-19 Pandemic #MMPMID33622217
  • Azapira N; Pourjafar S; Habibi A; Tayebi L; Keshtkar S; Kaviani M
  • Exp Clin Transplant 2022[Nov]; 20 (11): 980-983 PMID33622217show ga
  • The pandemic of severe acute respiratory syndrome coronavirus-2 infection has prompted the urgent need for novel therapeutic approaches, especially for patients in critically severe conditions. To date, the pathogenesis of COVID-19 is not completely understood, and finding an effective new drug is still inconclusive. Mesenchymal stromal cell-derived extracellular vesicles contain large amounts of proteins, messenger RNA, and microRNAs that act as vehicles that transfer the cargo between cells. These nanotherapeutic materials exert anti-inflammatory effects on the immune system, which are necessary for subsidence of acute inflammation and promotion of tissue repair and regeneration. Therefore, the consideration of mesenchymal stromal cell-derived extracellular vesicles as a new, safe, and effective therapeutic approach in the treatment of COVID-19 pneumonia is suggested.
  • |*COVID-19[MESH]
  • |*Extracellular Vesicles[MESH]
  • |*Mesenchymal Stem Cell Transplantation[MESH]
  • |*Mesenchymal Stem Cells/cytology[MESH]
  • |Humans[MESH]


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