Autophagosome maturation stymied by SARS-CoV-2 #MMPMID33621488
Yim WW; Mizushima N
Dev Cell 2021[Feb]; 56 (4): 400-402 PMID33621488show ga
Many pathogens are capable of disrupting autophagy within host cells. In this issue of Developmental Cell, Miao et al. discover that the SARS-CoV-2 protein ORF3a inhibits autophagosome-lysosome fusion by dysregulating the HOPS complex.