StatPearls-/-ä 2024[Jan]; ä (ä): ä PMID33620868show ga
Gastric lymphoma accounts for approximately 5% of gastric neoplasms but is the most common location for extranodal lymphomas, representing about 30% to 40% of extranodal lymphomas and 55% to 65% of lymphomas impacting the gastrointestinal tract. Predominantly, this category of malignancies includes mucosa-associated lymphoid tissue (MALT) lymphoma or diffuse large B-cell lymphoma (DLBCL), with much less common occurrences of mantle cell lymphoma and follicular lymphoma. Notably, over 90% of gastric MALT lymphomas are linked to Helicobacter pylori infections, making the treatment of H pylori a pivotal component in managing gastric lymphomas. The diagnostic assessment for gastric lymphomas encompasses endoscopic biopsies, endoscopic ultrasounds, computed tomography, magnetic resonance imaging, positron emission tomography, and immunohistochemical testing. Management strategies for gastric lymphomas encompass antibiotic therapy to eliminate H pylori, biotherapy or immunotherapy, chemotherapy, and radiation therapy.