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10.3389/fimmu.2021.602848 http://scihub22266oqcxt.onion/10.3389/fimmu.2021.602848 33613574!7886971!33613574     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33613574&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Front+Immunol 2021 ; 12 (?): 602848 Nephropedia Template TP {{tp|p=33613574|t=2021. Parallels in Sepsis and COVID-19 Conditions: Implications for Managing Severe COVID-19 |pdf=|usr=}}{{33613574}} gab.com Text Parallels in Sepsis and COVID-19 Conditions: Implications for Managing Severe COVID-19 JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=33613574 #FOAvip Sepsis is a life-threatening systemic illness attributed to a dysregulated host response to infection. Sepsis is a global burden killing ~11 million persons annually. In December 2019, a novel pneumonia condition termed coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged and has resulted in more than 1,535,982 deaths globally as of 8(th) December 2020. These two conditions share many pathophysiological and clinical features. Notably, both sepsis and COVID-19 patients experience consumptive thrombocytopenia, haemolytic anaemia, vascular microthrombosis, multi-organ dysfunction syndrome, coagulopathy, septic shock, respiratory failure, fever, leukopenia, hypotension, leukocytosis, high cytokine production and high predisposition to opportunistic infections. Considering the parallels in the immunopathogenesis and pathophysiological manifestations of sepsis and COVID-19, it is highly likely that sepsis care, which has a well-established history in most health systems, could inform on COVID-19 management. In view of this, the present perspective compares the immunopathogenesis and pathophysiology of COVID-19 and non-SARS-CoV-2 induced sepsis, and lessons from sepsis that can be applicable to COVID-19 management. Twit Text FOAVip Parallels in Sepsis and COVID-19 Conditions: Implications for Managing Severe COVID-19 ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=33613574 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33613574 #FOAvip English Wikipedia <ref>{{Cite pmid|33613574}}</ref> Parallels in Sepsis and COVID-19 Conditions: Implications for Managing Severe COVID-19 #MMPMID33613574 Olwal CO; Nganyewo NN; Tapela K; Djomkam Zune AL; Owoicho O; Bediako Y; Duodu S Front Immunol 2021[]; 12 (?): 602848 PMID33613574show ga Sepsis is a life-threatening systemic illness attributed to a dysregulated host response to infection. Sepsis is a global burden killing ~11 million persons annually. In December 2019, a novel pneumonia condition termed coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged and has resulted in more than 1,535,982 deaths globally as of 8(th) December 2020. These two conditions share many pathophysiological and clinical features. Notably, both sepsis and COVID-19 patients experience consumptive thrombocytopenia, haemolytic anaemia, vascular microthrombosis, multi-organ dysfunction syndrome, coagulopathy, septic shock, respiratory failure, fever, leukopenia, hypotension, leukocytosis, high cytokine production and high predisposition to opportunistic infections. Considering the parallels in the immunopathogenesis and pathophysiological manifestations of sepsis and COVID-19, it is highly likely that sepsis care, which has a well-established history in most health systems, could inform on COVID-19 management. In view of this, the present perspective compares the immunopathogenesis and pathophysiology of COVID-19 and non-SARS-CoV-2 induced sepsis, and lessons from sepsis that can be applicable to COVID-19 management. |Animals[MESH] |COVID-19/*diagnosis/therapy[MESH] |Cytokine Release Syndrome[MESH] |Humans[MESH] |Hypovolemia[MESH] |Immune Tolerance[MESH] |Respiratory Insufficiency[MESH] |SARS-CoV-2/*physiology[MESH] |Sepsis/*diagnosis/therapy[MESH]Parallels in Sepsis and COVID-19 Conditions: Implications for Managing(epmc).pdf DeepDyve Pubget Overpricing