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10.2116/analsci.21N004

http://scihub22266oqcxt.onion/10.2116/analsci.21N004
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33612558!ä!33612558

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suck abstract from ncbi


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pmid33612558      Anal+Sci 2021 ; 37 (9): 1301-1304
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  • Optimization of Analytical Procedure for In-hospital Rapid Quantification of Serum Level of Favipiravir in the Pharmacological Treatment of COVID-19 #MMPMID33612558
  • Moriiwa Y; Morikawa G; Okazawa K; Yanagida A
  • Anal Sci 2021[Sep]; 37 (9): 1301-1304 PMID33612558show ga
  • An in-hospital rapid method for quantifying the serum level of favipiravir (FPV) in the pharmacological treatment of COVID-19 was developed by an appropriate combination of a solid-phase extraction treatment and a reversed-phase HPLC/UV detection system. The quantification method was well-validated and applied to measuring the serum FPV level in a clinical practice at a general hospital that accepts COVID-19 patients. Furthermore, an analysis of data from our preliminary interaction analysis revealed, for the first time, that FPV selectively forms complexes with ferric (Fe(3+)) and cupric (Cu(2+)) ions.
  • |*COVID-19 Drug Treatment[MESH]
  • |*Hospitals[MESH]
  • |Amides/*blood/therapeutic use[MESH]
  • |Blood Chemical Analysis/*methods[MESH]
  • |COVID-19/blood[MESH]
  • |Chromatography, High Pressure Liquid[MESH]
  • |Humans[MESH]
  • |Pyrazines/*blood/therapeutic use[MESH]


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