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10.1016/j.ijmmb.2020.12.009 http://scihub22266oqcxt.onion/10.1016/j.ijmmb.2020.12.009 33610247!7834072!33610247     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Indian+J+Med+Microbiol 2021 ; 39 (1): 133-135 Nephropedia Template TP {{tp|p=33610247|t=2021. Cycle threshold values versus reverse transcription-polymerase chain reaction positivity in COVID-19 de-isolation |pdf=|usr=}}{{33610247}} gab.com Text Cycle threshold values versus reverse transcription-polymerase chain reaction positivity in COVID-19 de-isolation JO: Indian J Med Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=33610247 #FOAvip In the modern COVID-19 pandemic, reverse transcription-polymerase chain reaction (RT-PCR) positivity has a major role in the diagnosis of the disease. However, in deciding the patient's discharge or de-isolation, its role is still debatable. We are, hereby, describing three cases (an intern, a nursing officer and a caretaker of another patient) where only RT-PCR could not help much since it was persistently positive for >20 days of the illness course. Instead, the cycle threshold (Ct) values could have better correlated with the infectivity of COVID. We propose a rising trend (24 h apart) and absolute Ct value?>?25, instead of RT-PCR negativity (which was taken as Ct value?>?36 in our laboratory), to be used in deciding the infective potential of the patients, their discharge from the hospital and de-isolation of the patients. This will help in the timely discharge of patients from health-care institutions and home isolation, which, as a result, will lead to optimal utilisation of the limited hospital resources we have available in the line of the ongoing pandemic. Future studies are required to define the exact cut-off of Ct value for de-isolation purposes. Twit Text FOAVip Cycle threshold values versus reverse transcription-polymerase chain reaction positivity in COVID-19 de-isolation ????Indian J Med Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=33610247 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33610247 #FOAvip English Wikipedia <ref>{{Cite pmid|33610247}}</ref> Cycle threshold values versus reverse transcription-polymerase chain reaction positivity in COVID-19 de-isolation #MMPMID33610247 Kapoor M; Kalita D; Panda PK Indian J Med Microbiol 2021[Jan]; 39 (1): 133-135 PMID33610247show ga In the modern COVID-19 pandemic, reverse transcription-polymerase chain reaction (RT-PCR) positivity has a major role in the diagnosis of the disease. However, in deciding the patient's discharge or de-isolation, its role is still debatable. We are, hereby, describing three cases (an intern, a nursing officer and a caretaker of another patient) where only RT-PCR could not help much since it was persistently positive for >20 days of the illness course. Instead, the cycle threshold (Ct) values could have better correlated with the infectivity of COVID. We propose a rising trend (24 h apart) and absolute Ct value?>?25, instead of RT-PCR negativity (which was taken as Ct value?>?36 in our laboratory), to be used in deciding the infective potential of the patients, their discharge from the hospital and de-isolation of the patients. This will help in the timely discharge of patients from health-care institutions and home isolation, which, as a result, will lead to optimal utilisation of the limited hospital resources we have available in the line of the ongoing pandemic. Future studies are required to define the exact cut-off of Ct value for de-isolation purposes. |*Reverse Transcriptase Polymerase Chain Reaction/methods/standards[MESH] |Adult[MESH] |COVID-19/*diagnosis/epidemiology/*virology[MESH] |Disease Management[MESH] |Female[MESH] |Hospitalization[MESH] |Humans[MESH] |Male[MESH] |SARS-CoV-2/*genetics/isolation & purification[MESH] |Severity of Illness Index[MESH] |Symptom Assessment[MESH]Cycle threshold values versus reverse transcription-polymerase chain r(epmc).pdf DeepDyve Pubget Overpricing