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10.1016/j.ejmech.2021.113220 http://scihub22266oqcxt.onion/10.1016/j.ejmech.2021.113220 33609889!7995244!33609889     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Eur+J+Med+Chem 2021 ; 215 (ä): 113220 Nephropedia Template TP {{tp|p=33609889|t=2021. Synthetic and medicinal perspective of quinolines as antiviral agents |pdf=|usr=}}{{33609889}} gab.com Text Synthetic and medicinal perspective of quinolines as antiviral agents JO: Eur J Med Chem http://www.kidney.de/pget.php?&tw=1&pmid=33609889 #FOAvip In current scenario, various heterocycles have come up exhibiting crucial role in various medicinal agents which are valuable for mankind. Out of diverse range of heterocycle, quinoline scaffold have been proved to play an important role in broad range of biological activities. Several drug molecules bearing a quinoline molecule with useful anticancer, antibacterial activities etc have been marketed such as chloroquine, saquinavir etc. Owing to their broad spectrum biological role, various synthetic strategies such as Skraup reaction, Combes reaction etc. has been developed by the researchers all over the world. But still the synthetic methods are associated with various limitations as formation of side products, use of expensive metal catalysts. Thus, several efforts to develop an efficient and cost effective synthetic protocol are still carried out till date. Moreover, quinoline scaffold displays remarkable antiviral activity. Therefore, in this review we have made an attempt to describe recent synthetic protocols developed by various research groups along with giving a complete explanation about the role of quinoline derivatives as antiviral agent. Quinoline derivatives were found potent against various strains of viruses like zika virus, enterovirus, herpes virus, human immunodeficiency virus, ebola virus, hepatitis C virus, SARS virus and MERS virus etc. Twit Text FOAVip Synthetic and medicinal perspective of quinolines as antiviral agents ????Eur J Med Chem http://www.kidney.de/pget.php?&tw=1&pmid=33609889 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33609889 #FOAvip English Wikipedia <ref>{{Cite pmid|33609889}}</ref> Synthetic and medicinal perspective of quinolines as antiviral agents #MMPMID33609889 Kaur R; Kumar K Eur J Med Chem 2021[Apr]; 215 (ä): 113220 PMID33609889show ga In current scenario, various heterocycles have come up exhibiting crucial role in various medicinal agents which are valuable for mankind. Out of diverse range of heterocycle, quinoline scaffold have been proved to play an important role in broad range of biological activities. Several drug molecules bearing a quinoline molecule with useful anticancer, antibacterial activities etc have been marketed such as chloroquine, saquinavir etc. Owing to their broad spectrum biological role, various synthetic strategies such as Skraup reaction, Combes reaction etc. has been developed by the researchers all over the world. But still the synthetic methods are associated with various limitations as formation of side products, use of expensive metal catalysts. Thus, several efforts to develop an efficient and cost effective synthetic protocol are still carried out till date. Moreover, quinoline scaffold displays remarkable antiviral activity. Therefore, in this review we have made an attempt to describe recent synthetic protocols developed by various research groups along with giving a complete explanation about the role of quinoline derivatives as antiviral agent. Quinoline derivatives were found potent against various strains of viruses like zika virus, enterovirus, herpes virus, human immunodeficiency virus, ebola virus, hepatitis C virus, SARS virus and MERS virus etc. |Animals[MESH] |Antiviral Agents/chemical synthesis/pharmacology/*therapeutic use[MESH] |Cell Line, Tumor[MESH] |Humans[MESH] |Quinolines/chemical synthesis/pharmacology/*therapeutic use[MESH] |Virus Diseases/*drug therapy[MESH]Synthetic and medicinal perspective of quinolines as antiviral agents (epmc).pdf DeepDyve Pubget Overpricing