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10.1038/s41598-021-83110-6 http://scihub22266oqcxt.onion/10.1038/s41598-021-83110-6 33608566!7895922!33608566     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2021 ; 11 (1): 4243 Nephropedia Template TP {{tp|p=33608566|t=2021. Immune transcriptomes of highly exposed SARS-CoV-2 asymptomatic seropositive versus seronegative individuals from the Ischgl community |pdf=|usr=}}{{33608566}} gab.com Text Immune transcriptomes of highly exposed SARS-CoV-2 asymptomatic seropositive versus seronegative individuals from the Ischgl community JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33608566 #FOAvip SARS-CoV-2 infection ranges from asymptomatic to severe with lingering symptomatology in some. This prompted investigation of whether or not asymptomatic disease results in measurable immune activation post-infection. Immune activation following asymptomatic SARS-CoV-2 infection was characterized through a comparative investigation of the immune cell transcriptomes from 43 asymptomatic seropositive and 52 highly exposed seronegative individuals from the same community 4-6 weeks following a superspreading event. Few of the 95 individuals had underlying health issues. One seropositive individual reported Cystic Fibrosis and one individual reported Incontinentia pigmenti. No evidence of immune activation was found in asymptomatic seropositive individuals with the exception of the Cystic Fibrosis patient. There were no statistically significant differences in immune transcriptomes between asymptomatic seropositive and highly exposed seronegative individuals. Four positive controls, mildly symptomatic seropositive individuals whose blood was examined 3 weeks following infection, showed immune activation. Negative controls were four seronegative individuals from neighboring communities without COVID-19. All individuals remained in their usual state of health through a five-month follow-up after sample collection. In summary, whole blood transcriptomes identified individual immune profiles within a community population and showed that asymptomatic infection within a super-spreading event was not associated with enduring immunological activation. Twit Text FOAVip Immune transcriptomes of highly exposed SARS-CoV-2 asymptomatic seropositive versus seronegative individuals from the Ischgl community ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33608566 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33608566 #FOAvip English Wikipedia <ref>{{Cite pmid|33608566}}</ref> Immune transcriptomes of highly exposed SARS-CoV-2 asymptomatic seropositive versus seronegative individuals from the Ischgl community #MMPMID33608566 Lee HK; Knabl L; Pipperger L; Volland A; Furth PA; Kang K; Smith HE; Knabl L Sr; Bellmann R; Bernhard C; Kaiser N; Ganzer H; Strohle M; Walser A; von Laer D; Hennighausen L Sci Rep 2021[Feb]; 11 (1): 4243 PMID33608566show ga SARS-CoV-2 infection ranges from asymptomatic to severe with lingering symptomatology in some. This prompted investigation of whether or not asymptomatic disease results in measurable immune activation post-infection. Immune activation following asymptomatic SARS-CoV-2 infection was characterized through a comparative investigation of the immune cell transcriptomes from 43 asymptomatic seropositive and 52 highly exposed seronegative individuals from the same community 4-6 weeks following a superspreading event. Few of the 95 individuals had underlying health issues. One seropositive individual reported Cystic Fibrosis and one individual reported Incontinentia pigmenti. No evidence of immune activation was found in asymptomatic seropositive individuals with the exception of the Cystic Fibrosis patient. There were no statistically significant differences in immune transcriptomes between asymptomatic seropositive and highly exposed seronegative individuals. Four positive controls, mildly symptomatic seropositive individuals whose blood was examined 3 weeks following infection, showed immune activation. Negative controls were four seronegative individuals from neighboring communities without COVID-19. All individuals remained in their usual state of health through a five-month follow-up after sample collection. In summary, whole blood transcriptomes identified individual immune profiles within a community population and showed that asymptomatic infection within a super-spreading event was not associated with enduring immunological activation. |Adaptive Immunity/genetics[MESH] |Adolescent[MESH] |Adult[MESH] |Aged[MESH] |Antibodies, Viral/blood/isolation & purification[MESH] |Asymptomatic Infections[MESH] |Austria[MESH] |COVID-19 Serological Testing/statistics & numerical data[MESH] |COVID-19/blood/diagnosis/*immunology/transmission[MESH] |Child[MESH] |Child, Preschool[MESH] |Contact Tracing/statistics & numerical data[MESH] |Family Characteristics[MESH] |Female[MESH] |Follow-Up Studies[MESH] |Host Microbial Interactions/genetics/immunology[MESH] |Humans[MESH] |Immunity, Innate/genetics[MESH] |Infant[MESH] |Male[MESH] |Middle Aged[MESH] |RNA-Seq/statistics & numerical data[MESH] |SARS-CoV-2/*immunology/isolation & purification[MESH] |Transcriptome/*immunology[MESH]Immune transcriptomes of highly exposed SARS-CoV-2 asymptomatic seropo(epmc).pdf DeepDyve Pubget Overpricing