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10.1016/j.jviromet.2021.114102 http://scihub22266oqcxt.onion/10.1016/j.jviromet.2021.114102 33607117!7885623!33607117     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33607117&cmd=llinks): Failed to open stream: HTTP request failed! 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Comparative analysis of point-of-care, high-throughput and laboratory-developed SARS-CoV-2 nucleic acid amplification tests (NATs) |pdf=|usr=}}{{33607117}} gab.com Text Comparative analysis of point-of-care, high-throughput and laboratory-developed SARS-CoV-2 nucleic acid amplification tests (NATs) JO: J Virol Methods http://www.kidney.de/pget.php?&tw=1&pmid=33607117 #FOAvip Multiple nucleic acid amplification tests (NATs) are available for the detection of SARS-CoV-2 in clinical specimens, including Laboratory Developed Tests (LDT), commercial high-throughput assays and point-of-care tests. Some assays were just recently released and there is limited data on their clinical performance. We compared the Xpert(R) Xpress SARS-CoV-2 (Cepheid) and Vivalytic VRI Panel (Schnelltest COVID-19) (Bosch) point-of-care tests with four high-throughput assays and one LDT, the cobas(R) SARS-CoV-2 test (Roche), the Allplex 2019-nCoV Assay (Seegene), the SARS-CoV-2 AMP (Abbott) Kit, the RealStar(R) SARS-CoV-2 RT-PCR Kit 1.0 (altona) as well as an assay using a SARS-CoV-2 RdRP gene specific primer and probe set. Samples from patients with confirmed SARS-CoV-2 infection, samples from the first and second SARS-CoV-2-PCR External Quality Assessment (EQA) (INSTAND e.V.) and a 10-fold serial dilution of a SARS-CoV-2 cell culture (SARS-CoV-2 Frankfurt 1) supernatant were examined. We determined that the NAT assays examined had a high specificity. Assays using the N gene as target demonstrated the highest sensitivity in the serial dilution panel, while all examined NAT assays showed a comparable sensitivity when testing clinical and EQA samples. Twit Text FOAVip Comparative analysis of point-of-care, high-throughput and laboratory-developed SARS-CoV-2 nucleic acid amplification tests (NATs) ????J Virol Methods http://www.kidney.de/pget.php?&tw=1&pmid=33607117 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33607117 #FOAvip English Wikipedia <ref>{{Cite pmid|33607117}}</ref> Comparative analysis of point-of-care, high-throughput and laboratory-developed SARS-CoV-2 nucleic acid amplification tests (NATs) #MMPMID33607117 Kohmer N; Rabenau HF; Hoehl S; Kortenbusch M; Ciesek S; Berger A J Virol Methods 2021[May]; 291 (ä): 114102 PMID33607117show ga Multiple nucleic acid amplification tests (NATs) are available for the detection of SARS-CoV-2 in clinical specimens, including Laboratory Developed Tests (LDT), commercial high-throughput assays and point-of-care tests. Some assays were just recently released and there is limited data on their clinical performance. We compared the Xpert(R) Xpress SARS-CoV-2 (Cepheid) and Vivalytic VRI Panel (Schnelltest COVID-19) (Bosch) point-of-care tests with four high-throughput assays and one LDT, the cobas(R) SARS-CoV-2 test (Roche), the Allplex 2019-nCoV Assay (Seegene), the SARS-CoV-2 AMP (Abbott) Kit, the RealStar(R) SARS-CoV-2 RT-PCR Kit 1.0 (altona) as well as an assay using a SARS-CoV-2 RdRP gene specific primer and probe set. Samples from patients with confirmed SARS-CoV-2 infection, samples from the first and second SARS-CoV-2-PCR External Quality Assessment (EQA) (INSTAND e.V.) and a 10-fold serial dilution of a SARS-CoV-2 cell culture (SARS-CoV-2 Frankfurt 1) supernatant were examined. We determined that the NAT assays examined had a high specificity. Assays using the N gene as target demonstrated the highest sensitivity in the serial dilution panel, while all examined NAT assays showed a comparable sensitivity when testing clinical and EQA samples. |*Point-of-Care Testing[MESH] |COVID-19 Nucleic Acid Testing/methods[MESH] |COVID-19 Testing/*methods[MESH] |COVID-19/*diagnosis[MESH] |Clinical Laboratory Techniques/methods[MESH] |High-Throughput Screening Assays/*methods[MESH] |Humans[MESH] |Nucleic Acid Amplification Techniques/methods[MESH] |SARS-CoV-2/genetics/*isolation & purification[MESH]Comparative analysis of point-of-care, high-throughput and laboratory-(epmc).pdf DeepDyve Pubget Overpricing