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10.1097/TP.0000000000003695

http://scihub22266oqcxt.onion/10.1097/TP.0000000000003695
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33606483!8222146!33606483
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suck abstract from ncbi


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pmid33606483      Transplantation 2021 ; 105 (7): 1445-1448
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  • Cycle Thresholds Among Solid Organ Transplant Recipients Testing Positive for SARS-CoV-2 #MMPMID33606483
  • Theodore DA; Greendyke WG; Miko B; Whittier S; Green DA; Shoucri S; Verna EC; Zucker J; Sobieszczyk ME; Aaron JG; Scully BE; Saiman L; Pereira M; Furuya EY
  • Transplantation 2021[Jul]; 105 (7): 1445-1448 PMID33606483show ga
  • BACKGROUND: The optimal duration of transmission-based precautions among immunocompromised patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unknown. METHODS: Retrospective review of patients with solid organ transplant with positive SARS-CoV-2 polymerase chain reaction result from nasopharyngeal specimens admitted to the hospital between March 13, 2020 and May 15, 2020. RESULTS: Twenty-one percent of solid organ transplant recipients with positive SARS-CoV-2 polymerase chain reaction detected >/=20 d after symptom onset (or after first positive test among asymptomatic individuals) had a low cycle threshold (ie, high viral load). The majority of these patients were asymptomatic or symptomatically improved. CONCLUSIONS: Solid organ transplant recipients may have prolonged high viral burden of SARS-CoV-2. Further data are needed to understand whether cycle threshold data can help inform strategies for prevention of healthcare-associated transmission of SARS-CoV-2 and for appropriate discontinuation of transmission-based precautions.
  • |*COVID-19 Testing[MESH]
  • |*Organ Transplantation[MESH]
  • |*Viral Load[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Asymptomatic Infections[MESH]
  • |COVID-19/diagnosis/prevention & control/transmission/*virology[MESH]
  • |Female[MESH]
  • |Follow-Up Studies[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Postoperative Complications/diagnosis/prevention & control/*virology[MESH]


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