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10.1080/07315724.2020.1869626

http://scihub22266oqcxt.onion/10.1080/07315724.2020.1869626
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suck abstract from ncbi


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pmid33605826      J+Am+Nutr+Assoc 2022 ; 41 (2): 201-206
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  • An Evaluation of Serum 25-Hydroxy Vitamin D Levels in Patients with COVID-19 in New York City #MMPMID33605826
  • Gavioli EM; Miyashita H; Hassaneen O; Siau E
  • J Am Nutr Assoc 2022[Feb]; 41 (2): 201-206 PMID33605826show ga
  • AIM: Deterioration of patients from COVID-19 is associated with cytokine release syndrome attributed to an elevation in pro-inflammatory cytokines. Vitamin D reduces proinflammatory cytokines, and has the possibility of reducing complications from respiratory tract illnesses. METHOD: This was a retrospective, observational, cohort study of patients with COVID-19 disease within a New York City Health System. Adult patients were included if they tested positive for SARS-CoV-2, and had a serum 25-hydroxy vitamin D level (25(OH)D) within the three previous months prior to their detected SARS-CoV-2 test. Patients were compared and evaluated based upon their 25(OH)D levels. The primary endpoints were hospitalization, need for oxygen support, and 90-day mortality. RESULTS: 437 COVID-19 patients were included [67 (IQR: 56-79) years] within this cohort. Deficient plasma 25(OH)D levels (<20 ng/ml) were associated with an increased likelihood of oxygen support [OR:2.23 (95% CI: 1.46-3.44, p = 0.0002)] from COVID-19. Deficient plasma 25(OH)D levels were not independently associated with 90-day mortality or risk of hospitalization. Hospitalization rates (98%), oxygen support (93%), and mortality rates (49%) were highest in patients who had 25(OH)D levels less than 10 ng/ml when compared to other 25(OH)D levels. CONCLUSION: Serum 25-hydroxy vitamin D levels may affect the need for oxygen support therapy in patients with COVID-19.
  • |*COVID-19/epidemiology[MESH]
  • |*Vitamin D Deficiency/epidemiology[MESH]
  • |Adult[MESH]
  • |Calcifediol[MESH]
  • |Cohort Studies[MESH]
  • |Cytokines[MESH]
  • |Humans[MESH]
  • |New York City/epidemiology[MESH]
  • |Oxygen[MESH]
  • |SARS-CoV-2[MESH]


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