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10.1021/acs.est.0c07721

http://scihub22266oqcxt.onion/10.1021/acs.est.0c07721
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33605140!ä!33605140

suck abstract from ncbi


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pmid33605140      Environ+Sci+Technol 2021 ; 55 (5): 2890-2898
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  • Quantifying Proximity, Confinement, and Interventions in Disease Outbreaks: A Decision Support Framework for Air-Transported Pathogens #MMPMID33605140
  • Bond TC; Bosco-Lauth A; Farmer DK; Francisco PW; Pierce JR; Fedak KM; Ham JM; Jathar SH; VandeWoude S
  • Environ Sci Technol 2021[Mar]; 55 (5): 2890-2898 PMID33605140show ga
  • The inability to communicate how infectious diseases are transmitted in human environments has triggered avoidance of interactions during the COVID-19 pandemic. We define a metric, Effective ReBreathed Volume (ERBV), that encapsulates how infectious pathogens, including SARS-CoV-2, transport in air. ERBV separates environmental transport from other factors in the chain of infection, allowing quantitative comparisons among situations. Particle size affects transport, removal onto surfaces, and elimination by mitigation measures, so ERBV is presented for a range of exhaled particle diameters: 1, 10, and 100 mum. Pathogen transport depends on both proximity and confinement. If interpersonal distancing of 2 m is maintained, then confinement, not proximity, dominates rebreathing after 10-15 min in enclosed spaces for all but 100 mum particles. We analyze strategies to reduce this confinement effect. Ventilation and filtration reduce person-to-person transport of 1 mum particles (ERBV(1)) by 13-85% in residential and office situations. Deposition to surfaces competes with intentional removal for 10 and 100 mum particles, so the same interventions reduce ERBV(10) by only 3-50%, and ERBV(100) is unaffected. Prior knowledge of size-dependent ERBV would help identify transmission modes and effective interventions. This framework supports mitigation decisions in emerging situations, even before other infectious parameters are known.
  • |*Air Pollution, Indoor[MESH]
  • |*COVID-19[MESH]
  • |Aerosols[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |SARS-CoV-2[MESH]


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