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10.1016/j.bj.2020.11.009 http://scihub22266oqcxt.onion/10.1016/j.bj.2020.11.009 33602633!7680063!33602633     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biomed+J 2021 ; 44 (1): 31-42 Nephropedia Template TP {{tp|p=33602633|t=2021. 3D culture models to study SARS-CoV-2 infectivity and antiviral candidates: From spheroids to bioprinting |pdf=|usr=}}{{33602633}} gab.com Text 3D culture models to study SARS-CoV-2 infectivity and antiviral candidates: From spheroids to bioprinting JO: Biomed J http://www.kidney.de/pget.php?&tw=1&pmid=33602633 #FOAvip The pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is receiving worldwide attention, due to the severity of the disease (COVID-19) that resulted in more than a million global deaths so far. The urgent need for vaccines and antiviral drugs is mobilizing the scientific community to develop strategies for studying the mechanisms of SARS-CoV-2 infection, replication kinetics, pathogenesis, host-virus interaction, and infection inhibition. In this work, we review the strategies of tissue engineering in the fabrication of three-dimensional (3D) models used in virology studies, which presented many advantages over conventional cell cultures, such as complex cytoarchitecture and a more physiological microenvironment. Scaffold-free (spheroids and organoids) and scaffold-based (3D scaffolding and 3D bioprinting) approach allow the biofabrication of more realistic models relevant to the pandemic, to be used as in vitro platforms for the development of new vaccines and therapies against COVID-19. Twit Text FOAVip 3D culture models to study SARS-CoV-2 infectivity and antiviral candidates: From spheroids to bioprinting ????Biomed J http://www.kidney.de/pget.php?&tw=1&pmid=33602633 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33602633 #FOAvip English Wikipedia <ref>{{Cite pmid|33602633}}</ref> 3D culture models to study SARS-CoV-2 infectivity and antiviral candidates: From spheroids to bioprinting #MMPMID33602633 de Melo BAG; Benincasa JC; Cruz EM; Maricato JT; Porcionatto MA Biomed J 2021[Mar]; 44 (1): 31-42 PMID33602633show ga The pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is receiving worldwide attention, due to the severity of the disease (COVID-19) that resulted in more than a million global deaths so far. The urgent need for vaccines and antiviral drugs is mobilizing the scientific community to develop strategies for studying the mechanisms of SARS-CoV-2 infection, replication kinetics, pathogenesis, host-virus interaction, and infection inhibition. In this work, we review the strategies of tissue engineering in the fabrication of three-dimensional (3D) models used in virology studies, which presented many advantages over conventional cell cultures, such as complex cytoarchitecture and a more physiological microenvironment. Scaffold-free (spheroids and organoids) and scaffold-based (3D scaffolding and 3D bioprinting) approach allow the biofabrication of more realistic models relevant to the pandemic, to be used as in vitro platforms for the development of new vaccines and therapies against COVID-19. |*Bioprinting[MESH] |*Spheroids, Cellular[MESH] |Angiotensin-Converting Enzyme 2/physiology[MESH] |Animals[MESH] |Antiviral Agents/pharmacology[MESH] |Humans[MESH] |Organoids[MESH] |SARS-CoV-2/drug effects/*pathogenicity[MESH] |Tissue Engineering/*methods[MESH]3D culture models to study SARS-CoV-2 infectivity and antiviral candid(epmc).pdf DeepDyve Pubget Overpricing