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10.1016/j.exer.2021.108501 http://scihub22266oqcxt.onion/10.1016/j.exer.2021.108501 33600811!7883706!33600811     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33600811&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Exp+Eye+Res 2021 ; 205 (?): 108501 Nephropedia Template TP {{tp|p=33600811|t=2021. High expression of SARS-CoV-2 entry factors in human conjunctival goblet cells |pdf=|usr=}}{{33600811}} gab.com Text High expression of SARS-CoV-2 entry factors in human conjunctival goblet cells JO: Exp Eye Res http://www.kidney.de/pget.php?&tw=1&pmid=33600811 #FOAvip The angiotensin-converting enzyme 2 (ACE2) receptor has been proved for SARS-CoV-2 cell entry after auxiliary cellular protease priming by transmembrane protease serine 2 (TMPRSS2), but the co-effect of this molecular mechanism was unknown. Here, single-cell sequencing was performed with human conjunctiva and the results have shown that ACE2 and TMPRSS2 were highly co-expressed in the goblet cells with genes involved in immunity process. This identification of conjunctival cell types which are permissive to virus entry would help to understand the process by which SARS-CoV-2 infection was established. These finding might be suggestive for COVID-19 control and protection. Twit Text FOAVip High expression of SARS-CoV-2 entry factors in human conjunctival goblet cells ????Exp Eye Res http://www.kidney.de/pget.php?&tw=1&pmid=33600811 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33600811 #FOAvip English Wikipedia <ref>{{Cite pmid|33600811}}</ref> High expression of SARS-CoV-2 entry factors in human conjunctival goblet cells #MMPMID33600811 Ma R; Gan L; Jiang S; Ding P; Chen D; Wu J; Qian J Exp Eye Res 2021[Apr]; 205 (?): 108501 PMID33600811show ga The angiotensin-converting enzyme 2 (ACE2) receptor has been proved for SARS-CoV-2 cell entry after auxiliary cellular protease priming by transmembrane protease serine 2 (TMPRSS2), but the co-effect of this molecular mechanism was unknown. Here, single-cell sequencing was performed with human conjunctiva and the results have shown that ACE2 and TMPRSS2 were highly co-expressed in the goblet cells with genes involved in immunity process. This identification of conjunctival cell types which are permissive to virus entry would help to understand the process by which SARS-CoV-2 infection was established. These finding might be suggestive for COVID-19 control and protection. |*Gene Expression Regulation[MESH] |COVID-19/*genetics/metabolism/pathology[MESH] |Conjunctiva/*metabolism/pathology[MESH] |Goblet Cells/*metabolism/pathology[MESH] |Humans[MESH] |Peptidyl-Dipeptidase A/biosynthesis/*genetics[MESH] |RNA/genetics[MESH] |SARS-CoV-2[MESH]High expression of SARS-CoV-2 entry factors in human conjunctival gobl(epmc).pdf DeepDyve Pubget Overpricing