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10.1089/mdr.2020.0489 http://scihub22266oqcxt.onion/10.1089/mdr.2020.0489 33600262!ä!33600262 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33600262&cmd=llinks): Failed to open stream: HTTP request failed! 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Multidrug-Resistant Infections and Outcome of Critically Ill Patients with Coronavirus Disease 2019: A Single Center Experience |pdf=|usr=}}{{33600262}} gab.com Text Multidrug-Resistant Infections and Outcome of Critically Ill Patients with Coronavirus Disease 2019: A Single Center Experience JO: Microb Drug Resist http://www.kidney.de/pget.php?&tw=1&pmid=33600262 #FOAvip Background: The aim of this study was to assess the drivers of multidrug-resistant (MDR) bacterial infection development in coronavirus disease 2019 (COVID-19) and its impact on patient outcome. Methods: Retrospective analysis on data from 32 consecutive patients with COVID-19, admitted to our intensive care unit (ICU) from March to May 2020. Outcomes considered were MDR infection and ICU mortality. Results: Fifty percent of patients developed an MDR infection during ICU stay after a median time of 8 [4-11] days. Most common MDR pathogens were carbapenem-resistant Klebsiella pneumoniae and Acinetobacter baumannii, causing bloodstream infections and pneumonia. MDR infections were linked to a higher length of ICU stay (p = 0.002), steroid therapy (p = 0.011), and associated with a lower ICU mortality (odds ratio: 0.439, 95% confidence interval: 0.251-0.763; p < 0.001). Low-dose aspirin intake was associated with both MDR infection (p = 0.043) and survival (p = 0.015). Among MDR patients, mortality was related with piperacillin-tazobactam use (p = 0.035) and an earlier onset of MDR infection (p = 0.042). Conclusions: MDR infections were a common complication in critically ill COVID-19 patients at our center. MDR risk was higher among those dwelling longer in the ICU and receiving steroids. However, MDR infections were not associated with a worse outcome. Twit Text FOAVip Multidrug-Resistant Infections and Outcome of Critically Ill Patients with Coronavirus Disease 2019: A Single Center Experience ????Microb Drug Resist http://www.kidney.de/pget.php?&tw=1&pmid=33600262 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33600262 #FOAvip English Wikipedia <ref>{{Cite pmid|33600262}}</ref> Multidrug-Resistant Infections and Outcome of Critically Ill Patients with Coronavirus Disease 2019: A Single Center Experience #MMPMID33600262 Karruli A; Boccia F; Gagliardi M; Patauner F; Ursi MP; Sommese P; De Rosa R; Murino P; Ruocco G; Corcione A; Andini R; Zampino R; Durante-Mangoni E Microb Drug Resist 2021[Sep]; 27 (9): 1167-1175 PMID33600262show ga Background: The aim of this study was to assess the drivers of multidrug-resistant (MDR) bacterial infection development in coronavirus disease 2019 (COVID-19) and its impact on patient outcome. Methods: Retrospective analysis on data from 32 consecutive patients with COVID-19, admitted to our intensive care unit (ICU) from March to May 2020. Outcomes considered were MDR infection and ICU mortality. Results: Fifty percent of patients developed an MDR infection during ICU stay after a median time of 8 [4-11] days. Most common MDR pathogens were carbapenem-resistant Klebsiella pneumoniae and Acinetobacter baumannii, causing bloodstream infections and pneumonia. MDR infections were linked to a higher length of ICU stay (p = 0.002), steroid therapy (p = 0.011), and associated with a lower ICU mortality (odds ratio: 0.439, 95% confidence interval: 0.251-0.763; p < 0.001). Low-dose aspirin intake was associated with both MDR infection (p = 0.043) and survival (p = 0.015). Among MDR patients, mortality was related with piperacillin-tazobactam use (p = 0.035) and an earlier onset of MDR infection (p = 0.042). Conclusions: MDR infections were a common complication in critically ill COVID-19 patients at our center. MDR risk was higher among those dwelling longer in the ICU and receiving steroids. However, MDR infections were not associated with a worse outcome. |*Drug Resistance, Multiple, Bacterial[MESH] |Acinetobacter Infections/drug therapy/microbiology/*mortality/virology[MESH] |Acinetobacter baumannii/drug effects/growth & development/pathogenicity[MESH] |Adult[MESH] |Aged[MESH] |Anti-Bacterial Agents/therapeutic use[MESH] |Aspirin/therapeutic use[MESH] |COVID-19 Drug Treatment[MESH] |COVID-19/microbiology/*mortality/virology[MESH] |Carbapenems/therapeutic use[MESH] |Critical Illness[MESH] |Female[MESH] |Hospital Mortality[MESH] |Humans[MESH] |Intensive Care Units[MESH] |Klebsiella Infections/drug therapy/microbiology/*mortality/virology[MESH] |Klebsiella pneumoniae/drug effects/growth & development/pathogenicity[MESH] |Length of Stay/statistics & numerical data[MESH] |Male[MESH] |Middle Aged[MESH] |Opportunistic Infections/drug therapy/microbiology/*mortality/virology[MESH] |Piperacillin, Tazobactam Drug Combination/therapeutic use[MESH] |Pneumonia/drug therapy/microbiology/*mortality/virology[MESH] |Retrospective Studies[MESH] |SARS-CoV-2/drug effects/*pathogenicity/physiology[MESH] |Steroids/therapeutic use[MESH] |Survival Analysis[MESH]Multidrug-Resistant Infections and Outcome of Critically Ill Patients (epmc).pdf DeepDyve Pubget Overpricing