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10.1186/s13567-020-00883-w http://scihub22266oqcxt.onion/10.1186/s13567-020-00883-w 33597007!7888150!33597007     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Vet+Res 2021 ; 52 (1): 26 Nephropedia Template TP {{tp|p=33597007|t=2021. PEDV infection in neonatal piglets through the nasal cavity is mediated by subepithelial CD3(+) T cells |pdf=|usr=}}{{33597007}} gab.com Text PEDV infection in neonatal piglets through the nasal cavity is mediated by subepithelial CD3(+) T cells JO: Vet Res http://www.kidney.de/pget.php?&tw=1&pmid=33597007 #FOAvip Porcine epidemic diarrhea virus (PEDV) primarily infects neonatal piglets causing catastrophic effects on the global pig farming industry. PEDV infects piglets through the nasal cavity, a process in which dendritic cells (DCs) play an important role. However, neonatal piglets have fewer nasal DCs. This study found that subepithelial CD3(+) T cells mediated PEDV invasion through the nasal cavity in neonatal piglets. PEDV could replicate in the nasal epithelial cells (NECs) isolated from the nasal cavity of neonatal piglets. Infection of NECs with PEDV could induce antiviral and inflammatory cytokines at the late stage. The infected NECs mediated transfer of virus to CD3(+) T cells distributed in the subepithelial of the nasal cavity via cell-to-cell contact. The infected CD3(+) T cells could migrate to the intestine via blood circulation, causing intestinal infection in neonatal piglets. Thus, the findings of this study indicate the importance of CD3(+)T cells in the dissemination of PEDV from the nasal cavity to the intestinal mucosa in neonatal piglets. Twit Text FOAVip PEDV infection in neonatal piglets through the nasal cavity is mediated by subepithelial CD3(+) T cells ????Vet Res http://www.kidney.de/pget.php?&tw=1&pmid=33597007 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33597007 #FOAvip English Wikipedia <ref>{{Cite pmid|33597007}}</ref> PEDV infection in neonatal piglets through the nasal cavity is mediated by subepithelial CD3(+) T cells #MMPMID33597007 Yuan C; Jin Y; Li Y; Zhang E; Zhang P; Yang Q Vet Res 2021[Feb]; 52 (1): 26 PMID33597007show ga Porcine epidemic diarrhea virus (PEDV) primarily infects neonatal piglets causing catastrophic effects on the global pig farming industry. PEDV infects piglets through the nasal cavity, a process in which dendritic cells (DCs) play an important role. However, neonatal piglets have fewer nasal DCs. This study found that subepithelial CD3(+) T cells mediated PEDV invasion through the nasal cavity in neonatal piglets. PEDV could replicate in the nasal epithelial cells (NECs) isolated from the nasal cavity of neonatal piglets. Infection of NECs with PEDV could induce antiviral and inflammatory cytokines at the late stage. The infected NECs mediated transfer of virus to CD3(+) T cells distributed in the subepithelial of the nasal cavity via cell-to-cell contact. The infected CD3(+) T cells could migrate to the intestine via blood circulation, causing intestinal infection in neonatal piglets. Thus, the findings of this study indicate the importance of CD3(+)T cells in the dissemination of PEDV from the nasal cavity to the intestinal mucosa in neonatal piglets. |Animals[MESH] |Animals, Newborn[MESH] |CD3 Complex/*metabolism[MESH] |Cell Line[MESH] |Chlorocebus aethiops[MESH] |Coronavirus Infections/immunology/*veterinary/virology[MESH] |Nasal Cavity/*physiology/virology[MESH] |Porcine epidemic diarrhea virus/*physiology[MESH] |Swine[MESH] |Swine Diseases/*immunology/virology[MESH] |T-Lymphocytes/*physiology[MESH] |Vero Cells[MESH]PEDV infection in neonatal piglets through the nasal cavity is mediate(epmc).pdf DeepDyve Pubget Overpricing