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10.1016/j.diagmicrobio.2021.115340

http://scihub22266oqcxt.onion/10.1016/j.diagmicrobio.2021.115340
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suck abstract from ncbi


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pmid33596485      Diagn+Microbiol+Infect+Dis 2021 ; 100 (2): 115340
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  • Available COVID-19 serial seroconversion panel for validation of SARS-CoV-2 antibody assays #MMPMID33596485
  • Belda F; Lopez-Martinez M; Torres N; Cherenzia R; Crowley M
  • Diagn Microbiol Infect Dis 2021[Jun]; 100 (2): 115340 PMID33596485show ga
  • Seroconversion panels are an important tool for investigating antibody responses and developing serological assays. A seroconversion panel was generated from a single SARS-CoV-2 positive plasma donor over 87 days. This seroconversion panel was tested against 6 SARS-CoV-2 antibody tests (IgG, IgM, and total Ig). All test kits utilized recombinant antigens that are specific to SARS-CoV-2. The seroconversion panel showed IgG responses for SARS-CoV-2 after day 50. IgM levels peaked on day 50 (prior to IgG) and declined in subsequent samples. This seroconversion panel is a useful tool for validation of SARS-CoV-2 antibody assays.
  • |*Seroconversion[MESH]
  • |Antibodies, Viral/blood[MESH]
  • |COVID-19 Serological Testing/*methods[MESH]
  • |COVID-19/*immunology[MESH]
  • |Convalescence[MESH]
  • |Enzyme-Linked Immunosorbent Assay[MESH]
  • |Humans[MESH]
  • |Immunoglobulin G/blood[MESH]
  • |Immunoglobulin M/blood[MESH]
  • |Reproducibility of Results[MESH]


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