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10.1371/journal.pone.0247041 http://scihub22266oqcxt.onion/10.1371/journal.pone.0247041 33596245!7888592!33596245     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       PLoS+One 2021 ; 16 (2): e0247041 Nephropedia Template TP {{tp|p=33596245|t=2021. 16S rRNA gene sequencing of rectal swab in patients affected by COVID-19 |pdf=|usr=}}{{33596245}} gab.com Text 16S rRNA gene sequencing of rectal swab in patients affected by COVID-19 JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=33596245 #FOAvip COronaVIrus Disease-2019 (COVID-19) is a pandemic respiratory infection caused by a new betacoronavirus, the Severe Acute Respiratory Syndrome-CoronaVirus-2 (SARS-CoV-2). Few data are reported on the gut microbiota in COVID-19 patients. 16S rRNA gene sequencing was performed to reveal an altered composition of the gut microbiota in patients with COVID-19 pneumonia admitted in intensive care unit (ICU) (i-COVID19), or in infectious disease wards (w-COVID19) as compared to controls (CTRL). i-COVID19 patients showed a decrease of Chao1 index as compared to CTRL and w-COVID19 patients indicating that patients in ICU displayed a lower microbial richness while no change was observed as for Shannon Index. At the phylum level, an increase of Proteobacteria was detected in w-COVID19 patients as compared to CTRL. A decrease of Fusobacteria and Spirochetes has been found, with the latter decreased in i-COVID19 patients as compared to CTRL. Significant changes in gut microbial communities in patients with COVID-19 pneumonia with different disease severity compared to CTRL have been identified. Our preliminary data may provide valuable information and promising biomarkers for the diagnosis of the disease and, when validated in larger cohort, it could facilitate the stratification of patients based on the microbial signature. Twit Text FOAVip 16S rRNA gene sequencing of rectal swab in patients affected by COVID-19 ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=33596245 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33596245 #FOAvip English Wikipedia <ref>{{Cite pmid|33596245}}</ref> 16S rRNA gene sequencing of rectal swab in patients affected by COVID-19 #MMPMID33596245 Mazzarelli A; Giancola ML; Farina A; Marchioni L; Rueca M; Gruber CEM; Bartolini B; Ascoli Bartoli T; Maffongelli G; Capobianchi MR; Ippolito G; Di Caro A; Nicastri E; Pazienza V PLoS One 2021[]; 16 (2): e0247041 PMID33596245show ga COronaVIrus Disease-2019 (COVID-19) is a pandemic respiratory infection caused by a new betacoronavirus, the Severe Acute Respiratory Syndrome-CoronaVirus-2 (SARS-CoV-2). Few data are reported on the gut microbiota in COVID-19 patients. 16S rRNA gene sequencing was performed to reveal an altered composition of the gut microbiota in patients with COVID-19 pneumonia admitted in intensive care unit (ICU) (i-COVID19), or in infectious disease wards (w-COVID19) as compared to controls (CTRL). i-COVID19 patients showed a decrease of Chao1 index as compared to CTRL and w-COVID19 patients indicating that patients in ICU displayed a lower microbial richness while no change was observed as for Shannon Index. At the phylum level, an increase of Proteobacteria was detected in w-COVID19 patients as compared to CTRL. A decrease of Fusobacteria and Spirochetes has been found, with the latter decreased in i-COVID19 patients as compared to CTRL. Significant changes in gut microbial communities in patients with COVID-19 pneumonia with different disease severity compared to CTRL have been identified. Our preliminary data may provide valuable information and promising biomarkers for the diagnosis of the disease and, when validated in larger cohort, it could facilitate the stratification of patients based on the microbial signature. |Adult[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |Bacteria/genetics[MESH] |COVID-19/genetics/*microbiology/virology[MESH] |Cohort Studies[MESH] |Female[MESH] |Gastrointestinal Microbiome/*genetics[MESH] |Hospitalization[MESH] |Humans[MESH] |Intensive Care Units[MESH] |Italy/epidemiology[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |RNA, Ribosomal, 16S/*genetics[MESH]16S rRNA gene sequencing of rectal swab in patients affected by COVID-(epmc).pdf DeepDyve Pubget Overpricing