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10.1101/mcs.a006031 http://scihub22266oqcxt.onion/10.1101/mcs.a006031 33593727!8040733!33593727     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cold+Spring+Harb+Mol+Case+Stud 2021 ; 7 (2): ä Nephropedia Template TP {{tp|p=33593727|t=2021. The gut microbiome: a missing link in understanding the gastrointestinal manifestations of COVID-19?|pdf=|usr=}}{{33593727}} gab.com Text The gut microbiome: a missing link in understanding the gastrointestinal manifestations of COVID-19 JO: Cold Spring Harb Mol Case Stud http://www.kidney.de/pget.php?&tw=1&pmid=33593727 #FOAvip Coronavirus disease 2019 (COVID-19), which is caused by infection with SARS-CoV-2, presents with a broad constellation of both respiratory and nonrespiratory symptoms, although it is primarily considered a respiratory disease. Gastrointestinal symptoms-including nausea, abdominal pain, vomiting, and diarrhea-rank chief among these. When coupled with the presence of viral RNA in fecal samples, the presence of gastrointestinal symptoms raises relevant questions regarding whether SARS-CoV-2 can productively infect the upper or lower gastrointestinal tract. Despite the well-documented prevalence of gastrointestinal symptoms and the high rate of SARS-CoV-2 fecal RNA shedding, the biological, clinical, and epidemiological relevance of these findings is unclear. Furthermore, the isolation of replication-competent virus from fecal samples has not been reproducibly and rigorously demonstrated. Although SARS-CoV-2 shedding likely occurs in a high proportion of patients, gastrointestinal symptoms affect only a subset of individuals. Herein, we summarize what is known about gastrointestinal symptoms and fecal viral shedding in COVID-19, explore the role of the gut microbiome in other respiratory diseases, speculate on the role of the gut microbiota in COVID-19, and discuss potential future directions. Taking these concepts together, we propose that studying gut microbiota perturbations in COVID-19 will enhance our understanding of the symptomology and pathophysiology of this novel devastating disease. Twit Text FOAVip The gut microbiome: a missing link in understanding the gastrointestinal manifestations of COVID-19 ????Cold Spring Harb Mol Case Stud http://www.kidney.de/pget.php?&tw=1&pmid=33593727 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33593727 #FOAvip English Wikipedia <ref>{{Cite pmid|33593727}}</ref> The gut microbiome: a missing link in understanding the gastrointestinal manifestations of COVID-19? #MMPMID33593727 Brooks EF; Bhatt AS Cold Spring Harb Mol Case Stud 2021[Apr]; 7 (2): ä PMID33593727show ga Coronavirus disease 2019 (COVID-19), which is caused by infection with SARS-CoV-2, presents with a broad constellation of both respiratory and nonrespiratory symptoms, although it is primarily considered a respiratory disease. Gastrointestinal symptoms-including nausea, abdominal pain, vomiting, and diarrhea-rank chief among these. When coupled with the presence of viral RNA in fecal samples, the presence of gastrointestinal symptoms raises relevant questions regarding whether SARS-CoV-2 can productively infect the upper or lower gastrointestinal tract. Despite the well-documented prevalence of gastrointestinal symptoms and the high rate of SARS-CoV-2 fecal RNA shedding, the biological, clinical, and epidemiological relevance of these findings is unclear. Furthermore, the isolation of replication-competent virus from fecal samples has not been reproducibly and rigorously demonstrated. Although SARS-CoV-2 shedding likely occurs in a high proportion of patients, gastrointestinal symptoms affect only a subset of individuals. Herein, we summarize what is known about gastrointestinal symptoms and fecal viral shedding in COVID-19, explore the role of the gut microbiome in other respiratory diseases, speculate on the role of the gut microbiota in COVID-19, and discuss potential future directions. Taking these concepts together, we propose that studying gut microbiota perturbations in COVID-19 will enhance our understanding of the symptomology and pathophysiology of this novel devastating disease. |*Gastrointestinal Microbiome[MESH] |Abdominal Pain/diagnosis/*etiology/microbiology/pathology[MESH] |Animals[MESH] |COVID-19/*complications/diagnosis/microbiology/pathology[MESH] |Diarrhea/diagnosis/*etiology/microbiology/pathology[MESH] |Feces/microbiology/virology[MESH] |Humans[MESH] |Nausea/diagnosis/*etiology/microbiology/pathology[MESH] |SARS-CoV-2/isolation & purification[MESH]The gut microbiome: a missing link in understanding the gastrointestin(epmc).pdf DeepDyve Pubget Overpricing