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10.1002/jmv.26880

http://scihub22266oqcxt.onion/10.1002/jmv.26880
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33590901!8014583!33590901
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suck abstract from ncbi


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pmid33590901      J+Med+Virol 2021 ; 93 (5): 3176-3183
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  • Effect of a combination of nitazoxanide, ribavirin, and ivermectin plus zinc supplement (MANS NRIZ study) on the clearance of mild COVID-19 #MMPMID33590901
  • Elalfy H; Besheer T; El-Mesery A; El-Gilany AH; Soliman MA; Alhawarey A; Alegezy M; Elhadidy T; Hewidy AA; Zaghloul H; Neamatallah MAM; Raafat D; El-Emshaty WM; Abo El Kheir NY; El-Bendary M
  • J Med Virol 2021[May]; 93 (5): 3176-3183 PMID33590901show ga
  • This trial compared the rate and time of viral clearance in subjects receiving a combination of nitazoxanide, ribavirin, and ivermectin plus Zinc versus those receiving supportive treatment. This non-randomized controlled trial included 62 patients on the triple combination treatment versus 51 age- and sex-matched patients on routine supportive treatment. all of them confirmed cases by positive reverse-transcription polymerase chain reaction of a nasopharyngeal swab. Trial results showed that the clearance rates were 0% and 58.1% on the 7th day and 13.7% and 73.1% on the 15th day in the supportive treatment and combined antiviral groups, respectively. The cumulative clearance rates on the 15th day are 13.7% and 88.7% in the supportive treatment and combined antiviral groups, respectively. This trial concluded by stating that the combined use of nitazoxanide, ribavirin, and ivermectin plus zinc supplement effectively cleared the SARS-COV2 from the nasopharynx in a shorter time than symptomatic therapy.
  • |*COVID-19 Drug Treatment[MESH]
  • |*SARS-CoV-2[MESH]
  • |Adult[MESH]
  • |Antimetabolites/administration & dosage/therapeutic use[MESH]
  • |Antiparasitic Agents/administration & dosage/therapeutic use[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Ivermectin/administration & dosage/*therapeutic use[MESH]
  • |Male[MESH]
  • |Nitro Compounds/administration & dosage/*therapeutic use[MESH]
  • |Ribavirin/administration & dosage/*therapeutic use[MESH]
  • |Thiazoles/administration & dosage/*therapeutic use[MESH]
  • |Trace Elements/administration & dosage/therapeutic use[MESH]


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