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10.1186/s13052-021-00990-0

http://scihub22266oqcxt.onion/10.1186/s13052-021-00990-0
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33588905!7883952!33588905
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suck abstract from ncbi


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pmid33588905      Ital+J+Pediatr 2021 ; 47 (1): 32
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  • Could nutritional supplements act as therapeutic adjuvants in COVID-19? #MMPMID33588905
  • Costagliola G; Spada E; Comberiati P; Peroni DG
  • Ital J Pediatr 2021[Feb]; 47 (1): 32 PMID33588905show ga
  • BACKGROUND: The role of the immune system and inflammatory response in the pathogenesis of the severe manifestations of coronavirus disease 2019 (COVID-19) is well known. Currently, different therapies active on the immune system are used for the management of COVID-19. The involvement of the immune system also opens the opportunity for the use of nutritional supplements with antimicrobial and immunomodulatory activity. MAIN ASPECTS: Nutritional supplements with antimicrobial and immunomodulatory activity are promising therapeutic adjuvants for the treatment of COVID-19, and also for the prevention of viral spreading. In particular, the role of vitamin D, probiotics, lactoferrin, and zinc is of significant clinical interest, although there are only a few data on their use in COVID-19 patients. Their molecular actions, together with the results of studies performed on other respiratory infections, strongly suggest their potential utility in COVID-19. This article discusses the main properties of these nutritional supplements and their potential applicability in the prevention and treatment of COVID-19. CONCLUSION: The supplementation with vitamin D, probiotics, lactoferrin and zinc could have a role both in preventing SARS-CoV-2 infection and in mitigating the clinical course in infected patients, contributing in the prevention of immune-mediated organ damage.
  • |*COVID-19 Drug Treatment[MESH]
  • |*Dietary Supplements[MESH]
  • |COVID-19/*immunology[MESH]
  • |Humans[MESH]
  • |Lactoferrin/therapeutic use[MESH]
  • |Pandemics[MESH]
  • |Probiotics/therapeutic use[MESH]
  • |SARS-CoV-2[MESH]
  • |Vitamin D/therapeutic use[MESH]


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