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10.1016/j.media.2021.101978

http://scihub22266oqcxt.onion/10.1016/j.media.2021.101978
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suck abstract from ncbi


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pmid33588121      Med+Image+Anal 2021 ; 69 (ä): 101978
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  • A novel multiple instance learning framework for COVID-19 severity assessment via data augmentation and self-supervised learning #MMPMID33588121
  • Li Z; Zhao W; Shi F; Qi L; Xie X; Wei Y; Ding Z; Gao Y; Wu S; Liu J; Shi Y; Shen D
  • Med Image Anal 2021[Apr]; 69 (ä): 101978 PMID33588121show ga
  • How to fast and accurately assess the severity level of COVID-19 is an essential problem, when millions of people are suffering from the pandemic around the world. Currently, the chest CT is regarded as a popular and informative imaging tool for COVID-19 diagnosis. However, we observe that there are two issues - weak annotation and insufficient data that may obstruct automatic COVID-19 severity assessment with CT images. To address these challenges, we propose a novel three-component method, i.e., 1) a deep multiple instance learning component with instance-level attention to jointly classify the bag and also weigh the instances, 2) a bag-level data augmentation component to generate virtual bags by reorganizing high confidential instances, and 3) a self-supervised pretext component to aid the learning process. We have systematically evaluated our method on the CT images of 229 COVID-19 cases, including 50 severe and 179 non-severe cases. Our method could obtain an average accuracy of 95.8%, with 93.6% sensitivity and 96.4% specificity, which outperformed previous works.
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/*diagnostic imaging[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Deep Learning[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Infant, Newborn[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |SARS-CoV-2[MESH]
  • |Severity of Illness Index[MESH]
  • |Supervised Machine Learning[MESH]
  • |Tomography, X-Ray Computed[MESH]


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