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10.1097/PHM.0000000000001716

http://scihub22266oqcxt.onion/10.1097/PHM.0000000000001716
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33587451!ä!33587451

suck abstract from ncbi


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pmid33587451      Am+J+Phys+Med+Rehabil 2021 ; 100 (5): 413-418
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  • Low Thoracic Skeletal Muscle Area Is Not Associated With Negative Outcomes in Patients With COVID-19 #MMPMID33587451
  • Moctezuma-Velazquez P; Miranda-Zazueta G; Ortiz-Brizuela E; Gonzalez-Lara MF; Tamez-Torres KM; Roman-Montes CM; Diaz-Mejia BA; Perez-Garcia E; Villanueva-Reza M; Tovar-Mendez VH; Medrano-Borromeo C; Martinez-Valenzuela A; Jandete-Medina MA; Martinez-Guerra BA; Uscanga-Dominguez L; Sifuentes-Osornio J; Ponce-de-Leon A; Olivas-Martinez A; Moctezuma-Velazquez C
  • Am J Phys Med Rehabil 2021[May]; 100 (5): 413-418 PMID33587451show ga
  • OBJECTIVE: Sarcopenia has been related to negative outcomes in different clinical scenarios from critical illness to chronic conditions. The aim of this study was to verify whether there was an association between low skeletal muscle index and in-hospital mortality, intensive care unit admission, and invasive mechanical ventilation need in hospitalized patients with COVID-19. DESIGN: This was a retrospective cohort study of a referral center for COVID-19. We included all consecutive patients admitted to the hospital between February 26 and May 15, 2020, with a confirmed diagnosis of COVID-19. Skeletal muscle index was assessed from a transverse computed tomography image at the level of twelfth thoracic vertebra with National Institutes of Health ImageJ software, and statistical analysis was performed to find an association between skeletal muscle index and in-hospital mortality, need of invasive mechanical ventilation, and intensive care unit admission. RESULTS: We included 519 patients, the median age was 51 (42-61) yrs, and 115 patients (22%) had low skeletal muscle index. On multivariable analysis, skeletal muscle index was not associated with mortality, intensive care unit admission, or invasive mechanical ventilation need nor in a subanalysis of patients 65 yrs or older. CONCLUSIONS: Skeletal muscle index determined by computed tomography at the level of twelfth thoracic vertebra was not associated with negative outcomes in hospitalized patients with COVID-19.
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19/complications/*mortality/*therapy[MESH]
  • |Critical Care[MESH]
  • |Female[MESH]
  • |Hospital Mortality[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Muscle, Skeletal[MESH]
  • |Outcome Assessment, Health Care[MESH]
  • |Respiration, Artificial[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]
  • |Sarcopenia/*complications/diagnosis/mortality[MESH]


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