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10.1016/j.medcle.2020.11.006 http://scihub22266oqcxt.onion/10.1016/j.medcle.2020.11.006 33585689!7867393!33585689     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Med+Clin+(Engl+Ed) 2021 ; 156 (5): 221-228 Nephropedia Template TP {{tp|p=33585689|t=2021. Effectiveness of glucocorticoids in patients hospitalized for severe SARS-CoV-2 pneumonia |pdf=|usr=}}{{33585689}} gab.com Text Effectiveness of glucocorticoids in patients hospitalized for severe SARS-CoV-2 pneumonia JO: Med Clin (Engl Ed) http://www.kidney.de/pget.php?&tw=1&pmid=33585689 #FOAvip BACKGROUND: Several studies have reported the beneficial effect of glucocorticoids in the treatment of cytokine storm that occurs in patients with severe COVID-19. Various glucocorticoids regimens have been proposed. METHODS: Retrospective observational study that includes patients with severe SARS-CoV-2 pneumonia and compares admission to an Intensive Care Unit (ICU) or death during hospitalization in three groups of patients: no glucocorticoids treatment, use of glucocorticoids doses equivalent to less than 250?mg of prednisone daily and use of equivalent doses greater than or equal to 250?mg of prednisone daily. Multivariate analysis was performed using logistic regression, using the propensity index as a covariant. RESULTS: Of the 259 patients enrolled in the study, 67 (25.9%) had an unfavorable evolution, dying or requiring ICU admission. Comparative analyzes between different glucocorticoids treatments and the association with ICU admission or death were: glucocorticoids treatment (any dose) versus no glucocorticoids treatment (OR: 0.71 [0.30-1.66]), treatment with glucocorticoids (>/=250?mg prednisone daily) versus no glucocorticoids treatment (OR: 0.35 [0.11-1.08]) and glucocorticoids treatment (>/=250?mg prednisone daily) versus patients with glucocorticoids doses <250?mg prednisone daily or without glucocorticoids treatment (OR: 0.30 [0.10-0.88]). CONCLUSION: The results of this study show that patients with severe SARS-CoV-2 pneumonia treated with glucocorticoids pulses with equivalent doses of prednisone greater than or equal to 250?mg have a more favorable evolution (less mortality and less admission to ICU). Twit Text FOAVip Effectiveness of glucocorticoids in patients hospitalized for severe SARS-CoV-2 pneumonia ????Med Clin (Engl Ed) http://www.kidney.de/pget.php?&tw=1&pmid=33585689 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33585689 #FOAvip English Wikipedia <ref>{{Cite pmid|33585689}}</ref> Effectiveness of glucocorticoids in patients hospitalized for severe SARS-CoV-2 pneumonia #MMPMID33585689 Pascual Pareja JF; Garcia-Caballero R; Soler Rangel L; Vazquez-Ronda MA; Roa Franco S; Navarro Jimenez G; Moreno Palanco MA; Gonzalez-Ruano P; Lopez-Menchaca R; Ruiz-Seco P; Pagan Munoz B; Gomez Gomez A; Perez-Monte B; Fuerte Martinez R; Valle Lopez JL; Munoz Blanco A; Rabago Lorite I; Martinez Martin P; Serralta San Martin G; Gomez-Cerezo JF Med Clin (Engl Ed) 2021[Mar]; 156 (5): 221-228 PMID33585689show ga BACKGROUND: Several studies have reported the beneficial effect of glucocorticoids in the treatment of cytokine storm that occurs in patients with severe COVID-19. Various glucocorticoids regimens have been proposed. METHODS: Retrospective observational study that includes patients with severe SARS-CoV-2 pneumonia and compares admission to an Intensive Care Unit (ICU) or death during hospitalization in three groups of patients: no glucocorticoids treatment, use of glucocorticoids doses equivalent to less than 250?mg of prednisone daily and use of equivalent doses greater than or equal to 250?mg of prednisone daily. Multivariate analysis was performed using logistic regression, using the propensity index as a covariant. RESULTS: Of the 259 patients enrolled in the study, 67 (25.9%) had an unfavorable evolution, dying or requiring ICU admission. Comparative analyzes between different glucocorticoids treatments and the association with ICU admission or death were: glucocorticoids treatment (any dose) versus no glucocorticoids treatment (OR: 0.71 [0.30-1.66]), treatment with glucocorticoids (>/=250?mg prednisone daily) versus no glucocorticoids treatment (OR: 0.35 [0.11-1.08]) and glucocorticoids treatment (>/=250?mg prednisone daily) versus patients with glucocorticoids doses <250?mg prednisone daily or without glucocorticoids treatment (OR: 0.30 [0.10-0.88]). CONCLUSION: The results of this study show that patients with severe SARS-CoV-2 pneumonia treated with glucocorticoids pulses with equivalent doses of prednisone greater than or equal to 250?mg have a more favorable evolution (less mortality and less admission to ICU). äEffectiveness of glucocorticoids in patients hospitalized for severe S(epmc).pdf DeepDyve Pubget Overpricing