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10.5001/omj.2020.92

http://scihub22266oqcxt.onion/10.5001/omj.2020.92
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33585042!7868039!33585042
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suck abstract from ncbi

pmid33585042      Oman+Med+J 2021 ; 36 (1): e221
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  • Kidney Dysfunction among COVID-19 Patients in the United Arab Emirates #MMPMID33585042
  • Hachim IY; Hachim MY; Naeem KB; Hannawi H; Al Salmi I; Al-Zakwani I; Hannawi S
  • Oman Med J 2021[Jan]; 36 (1): e221 PMID33585042show ga
  • OBJECTIVES: We sought to determine the estimated glomerular filtration rate (eGFR) among patients with COVID-19 and to examine its correlation with different demographic, clinical, and laboratory characteristics. METHODS: This study examined patients diagnosed with COVID-19 and enrolled at Al Kuwait Hospital, Dubai, UAE. eGFR was calculated using the Modification of Diet in Renal Disease equation, 186 x (SCr mg/dL)(-1.154) x (age)(-0203) x 0.742 [if female] x 1.212 [if black], and compared for 250 COVID-19 cases and 153 non-COVID-19 controls. Analysis were performed using univariate statistics. RESULTS: The overall mean age of the cohort was 47.2+/-14.0 years, and 54.6% (n = 220) were males. The results showed that 45.3% of COVID-19 patients had mild-severe renal impairment, as reflected in the eGFR. When compared to patients with normal eGFR, those with severe renal impairment were older (62.5 vs. 40.2 years; p < 0.001), more likely to be male (100% vs. 71.1%; p = 0.016), and have comorbidities (90.9% vs. 40.0%; p < 0.001) including diabetes mellitus (72.7% vs. 21.5%; p < 0.001) and hypertension (72.7% vs. 25.2%; p = 0.003). They were also more likely to be associated with those that had severe (36.4% vs. 25.9%; p < 0.001) and critical (63.6% vs. 16.3%; p < 0.001) COVID-19 infection as well as intensive care unit admission (72.7% vs. 16.3%; p < 0.001). Correlational analysis showed a significant association between renal function indicators and different laboratory markers, including hematological indices and different liver enzymes. CONCLUSIONS: This is the first study to examine the renal function among COVID-19 cases in the Middle East. Nearly half of COVID-19 patients had moderate to severe renal impairment. Diabetes mellitus and hypertension were the most common underlying comorbidities associated with moderate-severe renal function impairment among COVID-19 patients.
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