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10.3389/fimmu.2020.607583 http://scihub22266oqcxt.onion/10.3389/fimmu.2020.607583 33584679!7878382!33584679     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Immunol 2020 ; 11 (ä): 607583 Nephropedia Template TP {{tp|p=33584679|t=2020. COVID-19: Imbalanced Immune Responses and Potential Immunotherapies |pdf=|usr=}}{{33584679}} gab.com Text COVID-19: Imbalanced Immune Responses and Potential Immunotherapies JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=33584679 #FOAvip The ongoing pandemic coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rapidly spreading and has resulted in grievous morbidity and mortality worldwide. Despite the high infectiousness of SARS-CoV-2, the majority of infected individuals are asymptomatic or have mild symptoms and could eventually recover as a result of their balanced immune function. On the contrary, immuno-compromised patients are prone to progress into severe or critical types underpinned by the entanglement of an overexuberant proinflammatory response and injured immune function. Therefore, well-coordinated innate and adaptive immune systems are pivotal to viral eradication and tissue repair. An in-depth understanding of the immunological processes underlying COVID-19 could facilitate rapidly identifying and choosing optimal immunotherapy for patients with severe SARS-CoV-2 infection. In this review, based on current immunological evidence, we describe potential immune mechanisms and discuss promising immunotherapies for COVID-19, including IL-6R blockades, convalescent plasma, intravenous gamma globulin, thymosin alpha1, corticosteroids, and type-I interferon, and recent advances in the development of COVID-19 vaccines. Twit Text FOAVip COVID-19: Imbalanced Immune Responses and Potential Immunotherapies ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=33584679 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33584679 #FOAvip English Wikipedia <ref>{{Cite pmid|33584679}}</ref> COVID-19: Imbalanced Immune Responses and Potential Immunotherapies #MMPMID33584679 Xie B; Zhang J; Li Y; Yuan S; Shang Y Front Immunol 2020[]; 11 (ä): 607583 PMID33584679show ga The ongoing pandemic coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rapidly spreading and has resulted in grievous morbidity and mortality worldwide. Despite the high infectiousness of SARS-CoV-2, the majority of infected individuals are asymptomatic or have mild symptoms and could eventually recover as a result of their balanced immune function. On the contrary, immuno-compromised patients are prone to progress into severe or critical types underpinned by the entanglement of an overexuberant proinflammatory response and injured immune function. Therefore, well-coordinated innate and adaptive immune systems are pivotal to viral eradication and tissue repair. An in-depth understanding of the immunological processes underlying COVID-19 could facilitate rapidly identifying and choosing optimal immunotherapy for patients with severe SARS-CoV-2 infection. In this review, based on current immunological evidence, we describe potential immune mechanisms and discuss promising immunotherapies for COVID-19, including IL-6R blockades, convalescent plasma, intravenous gamma globulin, thymosin alpha1, corticosteroids, and type-I interferon, and recent advances in the development of COVID-19 vaccines. |*COVID-19 Drug Treatment[MESH] |COVID-19/*immunology[MESH] |Humans[MESH] |Immunotherapy/*methods[MESH]COVID-19: Imbalanced Immune Responses and Potential Immunotherapies (epmc).pdf DeepDyve Pubget Overpricing