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Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Curr+Med+Sci 2021 ; 41 (1): 24-30 Nephropedia Template TP
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Corticosteroids Treatment of Patients with Coronavirus Disease 2019: A Propensity Score Matching Study #MMPMID33582901
Liang MY; Chen P; He M; Tang J; Li H; He XL; Zhou YY; Feng SW; Xue YE; Liu Y; Ma YL; Zhang JC
Curr Med Sci 2021[Feb]; 41 (1): 24-30 PMID33582901show ga
The role of corticosteroids in the treatment of Coronavirus disease 2019 (COVID-19) is controversial. In the present study, we evaluated the effects of adjuvant corticosteroids treatment on the outcome of patients with COVID-19 (n=966), using Propensity Score Matching to adjust for potential differences between the corticosteroids group (n=289) and the non-corticosteroids group (n=677). Analysis of data without adjusting differences in baseline characteristics indicated that the proportion of mechanical ventilation and the mortality was higher in the corticosteroids treatment group in total or severe/critical patients. The duration of viral shedding was longer in the non-corticosteroids treatment group in total or general/mild patients. After adjusting the difference between the corticosteroids and non-corticosteroids treatment group, the analysis revealed that the use of corticosteroids had no effect on the duration of viral shedding, in-hospital mortality or 28-day mortality.