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10.1007/s11596-021-2313-6

http://scihub22266oqcxt.onion/10.1007/s11596-021-2313-6
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33582901!7881915!33582901
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suck abstract from ncbi


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pmid33582901      Curr+Med+Sci 2021 ; 41 (1): 24-30
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  • Corticosteroids Treatment of Patients with Coronavirus Disease 2019: A Propensity Score Matching Study #MMPMID33582901
  • Liang MY; Chen P; He M; Tang J; Li H; He XL; Zhou YY; Feng SW; Xue YE; Liu Y; Ma YL; Zhang JC
  • Curr Med Sci 2021[Feb]; 41 (1): 24-30 PMID33582901show ga
  • The role of corticosteroids in the treatment of Coronavirus disease 2019 (COVID-19) is controversial. In the present study, we evaluated the effects of adjuvant corticosteroids treatment on the outcome of patients with COVID-19 (n=966), using Propensity Score Matching to adjust for potential differences between the corticosteroids group (n=289) and the non-corticosteroids group (n=677). Analysis of data without adjusting differences in baseline characteristics indicated that the proportion of mechanical ventilation and the mortality was higher in the corticosteroids treatment group in total or severe/critical patients. The duration of viral shedding was longer in the non-corticosteroids treatment group in total or general/mild patients. After adjusting the difference between the corticosteroids and non-corticosteroids treatment group, the analysis revealed that the use of corticosteroids had no effect on the duration of viral shedding, in-hospital mortality or 28-day mortality.
  • |*COVID-19 Drug Treatment[MESH]
  • |Adrenal Cortex Hormones/*administration & dosage/therapeutic use[MESH]
  • |Aged[MESH]
  • |Chemotherapy, Adjuvant[MESH]
  • |Female[MESH]
  • |Hospital Mortality[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Propensity Score[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2/drug effects/*physiology[MESH]


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