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10.1016/j.bbrc.2020.12.094

http://scihub22266oqcxt.onion/10.1016/j.bbrc.2020.12.094
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33581843!7833324!33581843
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suck abstract from ncbi


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pmid33581843      Biochem+Biophys+Res+Commun 2022 ; 591 (ä): 137-142
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  • Pathogenesis of COVID-19 and the quality control of nucleic acid detection #MMPMID33581843
  • Mao XD; Li T; Xu Z; Liu K
  • Biochem Biophys Res Commun 2022[Feb]; 591 (ä): 137-142 PMID33581843show ga
  • The new coronavirus pneumonia (COVID-19) epidemic spread rapidly throughout the world. Considering the strong infectivity and clustering of COVID-19, early detection of infectious cases is of great significance to control the epidemic. Nucleic acid testing (NAT) plays an important role in rapid laboratory diagnosis, treatment assessment, epidemic prevention and control of COVID-19. However, since COVID-19 is caused by a new emerging virus and NAT for COVID-19 has not been clinically applied before, false negative results inconsistent with clinical diagnosis have appeared in clinical practice. Therefore, it is urgent to improve the sensitivity of NAT for COVID-19. This study aimed to summarize the current situation and prospect of NAT based on the latest findings on COVID-19 infection. Also, the quality control of sample collection was discussed. Hopefully, this study could help to improve the effectiveness of NAT for COVID-19.
  • |COVID-19 Testing/*methods[MESH]
  • |COVID-19/*diagnosis/epidemiology/virology[MESH]
  • |Clinical Laboratory Techniques/methods[MESH]
  • |Genome, Viral/*genetics[MESH]
  • |Humans[MESH]
  • |Nucleic Acids/*genetics[MESH]
  • |Pandemics/prevention & control[MESH]
  • |Quality Control[MESH]
  • |SARS-CoV-2/*genetics/pathogenicity[MESH]
  • |Sensitivity and Specificity[MESH]
  • |Specimen Handling/methods[MESH]


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