Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.stemcr.2021.02.001 http://scihub22266oqcxt.onion/10.1016/j.stemcr.2021.02.001 33581053!7862909!33581053     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33581053&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Stem+Cell+Reports 2021 ; 16 (3): 428-436 Nephropedia Template TP {{tp|p=33581053|t=2021. Human Erythroid Progenitors Are Directly Infected by SARS-CoV-2: Implications for Emerging Erythropoiesis in Severe COVID-19 Patients |pdf=|usr=}}{{33581053}} gab.com Text Human Erythroid Progenitors Are Directly Infected by SARS-CoV-2: Implications for Emerging Erythropoiesis in Severe COVID-19 Patients JO: Stem Cell Reports http://www.kidney.de/pget.php?&tw=1&pmid=33581053 #FOAvip We document here that intensive care COVID-19 patients suffer a profound decline in hemoglobin levels but show an increase of circulating nucleated red cells, suggesting that SARS-CoV-2 infection either directly or indirectly induces stress erythropoiesis. We show that ACE2 expression peaks during erythropoiesis and renders erythroid progenitors vulnerable to infection by SARS-CoV-2. Early erythroid progenitors, defined as CD34(-)CD117(+)CD71(+)CD235a(-), show the highest levels of ACE2 and constitute the primary target cell to be infected during erythropoiesis. SARS-CoV-2 causes the expansion of colony formation by erythroid progenitors and can be detected in these cells after 2 weeks of the initial infection. Our findings constitute the first report of SARS-CoV-2 infectivity in erythroid progenitor cells and can contribute to understanding both the clinical symptoms of severe COVID-19 patients and how the virus can spread through the circulation to produce local inflammation in tissues, including the bone marrow. Twit Text FOAVip Human Erythroid Progenitors Are Directly Infected by SARS-CoV-2: Implications for Emerging Erythropoiesis in Severe COVID-19 Patients ????Stem Cell Reports http://www.kidney.de/pget.php?&tw=1&pmid=33581053 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33581053 #FOAvip English Wikipedia <ref>{{Cite pmid|33581053}}</ref> Human Erythroid Progenitors Are Directly Infected by SARS-CoV-2: Implications for Emerging Erythropoiesis in Severe COVID-19 Patients #MMPMID33581053 Huerga Encabo H; Grey W; Garcia-Albornoz M; Wood H; Ulferts R; Aramburu IV; Kulasekararaj AG; Mufti G; Papayannopoulos V; Beale R; Bonnet D Stem Cell Reports 2021[Mar]; 16 (3): 428-436 PMID33581053show ga We document here that intensive care COVID-19 patients suffer a profound decline in hemoglobin levels but show an increase of circulating nucleated red cells, suggesting that SARS-CoV-2 infection either directly or indirectly induces stress erythropoiesis. We show that ACE2 expression peaks during erythropoiesis and renders erythroid progenitors vulnerable to infection by SARS-CoV-2. Early erythroid progenitors, defined as CD34(-)CD117(+)CD71(+)CD235a(-), show the highest levels of ACE2 and constitute the primary target cell to be infected during erythropoiesis. SARS-CoV-2 causes the expansion of colony formation by erythroid progenitors and can be detected in these cells after 2 weeks of the initial infection. Our findings constitute the first report of SARS-CoV-2 infectivity in erythroid progenitor cells and can contribute to understanding both the clinical symptoms of severe COVID-19 patients and how the virus can spread through the circulation to produce local inflammation in tissues, including the bone marrow. |Angiotensin-Converting Enzyme 2/metabolism[MESH] |Animals[MESH] |COVID-19/metabolism/*virology[MESH] |Cell Line[MESH] |Chlorocebus aethiops[MESH] |Erythroid Precursor Cells/metabolism/*virology[MESH] |Erythropoiesis/*physiology[MESH] |Humans[MESH] |Inflammation/metabolism/virology[MESH] |SARS-CoV-2/*pathogenicity[MESH]Human Erythroid Progenitors Are Directly Infected by SARS-CoV-2: Impli(epmc).pdf DeepDyve Pubget Overpricing