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10.1080/21678421.2021.1883669

http://scihub22266oqcxt.onion/10.1080/21678421.2021.1883669
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33576710!ä!33576710

suck abstract from ncbi


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pmid33576710      Amyotroph+Lateral+Scler+Frontotemporal+Degener 2021 ; 22 (7-8): 505-507
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  • Increased worsening of amyotrophic lateral sclerosis patients during Covid-19-related lockdown in France #MMPMID33576710
  • Esselin F; De La Cruz E; Pageot N; Juntas-Morales R; Alphandery S; Camu W
  • Amyotroph Lateral Scler Frontotemporal Degener 2021[Nov]; 22 (7-8): 505-507 PMID33576710show ga
  • Covid-19-related lockdown (LD) in France precluded in-person follow-up in referral ALS centers. ALS patients' evolution and worsening before and during LD were studied to analyze its impact. A total of 84 patients were identified. The monthly rate of ALSFRS-R decline during LD was 1.06 +/- 1.42 and was significantly increased compared to the pre-LD period, 0.58 +/- 0.73, corresponding to an 83% increase (p = 0.007). Weight loss was unchanged between pre-LD and LD, gender and site of onset did not influence the rates of change of ALSFRS-R score. Several factors may be implicated in this increased severity of ALS during LD, such as psychological consequences of LD, interruptions of physiotherapy and speech therapy, or in-patient visits both to the tertiary center and the GP. Physicians and health authorities should be aware of that, in order to prevent the consequences of future sanitary restrictions.
  • |*Amyotrophic Lateral Sclerosis/epidemiology[MESH]
  • |*COVID-19[MESH]
  • |Communicable Disease Control[MESH]
  • |Disease Progression[MESH]
  • |France/epidemiology[MESH]
  • |Humans[MESH]


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