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suck abstract from ncbi


10.1038/s41467-021-21220-5

http://scihub22266oqcxt.onion/10.1038/s41467-021-21220-5
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33574258!7878793!33574258
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suck abstract from ncbi

pmid33574258      Nat+Commun 2021 ; 12 (1): 943
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  • Methodological quality of COVID-19 clinical research #MMPMID33574258
  • Jung RG; Di Santo P; Clifford C; Prosperi-Porta G; Skanes S; Hung A; Parlow S; Visintini S; Ramirez FD; Simard T; Hibbert B
  • Nat Commun 2021[Feb]; 12 (1): 943 PMID33574258show ga
  • The COVID-19 pandemic began in early 2020 with major health consequences. While a need to disseminate information to the medical community and general public was paramount, concerns have been raised regarding the scientific rigor in published reports. We performed a systematic review to evaluate the methodological quality of currently available COVID-19 studies compared to historical controls. A total of 9895 titles and abstracts were screened and 686 COVID-19 articles were included in the final analysis. Comparative analysis of COVID-19 to historical articles reveals a shorter time to acceptance (13.0[IQR, 5.0-25.0] days vs. 110.0[IQR, 71.0-156.0] days in COVID-19 and control articles, respectively; p < 0.0001). Furthermore, methodological quality scores are lower in COVID-19 articles across all study designs. COVID-19 clinical studies have a shorter time to publication and have lower methodological quality scores than control studies in the same journal. These studies should be revisited with the emergence of stronger evidence.
  • |*COVID-19[MESH]
  • |*Data Accuracy[MESH]
  • |*Periodicals as Topic[MESH]
  • |Animals[MESH]
  • |Clinical Studies as Topic[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Peer Review, Research[MESH]
  • |Research Design[MESH]


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