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Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Med+Hypotheses 2021 ; 148 (ä): 110508 Nephropedia Template TP
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Antihistamine and cationic amphiphilic drugs, old molecules as new tools against the COVID-19? #MMPMID33571758
Gitahy Falcao Faria C; Weiner L; Petrignet J; Hingray C; Ruiz De Pellon Santamaria A; Villoutreix BO; Beaune P; Leboyer M; Javelot H
Med Hypotheses 2021[Mar]; 148 (ä): 110508 PMID33571758show ga
Several studies have reported that certain psychoactive drugs could have a protective effect against SARS-CoV-2. Herein, we propose that antihistamines (anti-H1) and cationic amphiphilic drugs (CAD), specifically, have the capacity to disrupt virus entry and replication. In addition, several of these molecules have limited side effects and as such could be promising prophylactic candidates against SARS-CoV-2 infection.