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Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Adv+Clin+Exp+Med 2021 ; 30 (2): 153-156 Nephropedia Template TP
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The clinical value of high-density lipoprotein in the evaluation of new coronavirus pneumonia #MMPMID33571404
Huang S; Zhou C; Yuan Z; Xiao H; Wu X
Adv Clin Exp Med 2021[Feb]; 30 (2): 153-156 PMID33571404show ga
BACKGROUND: The new coronavirus pneumonia (NCP, COVID-19) outbreak began in Wuhan in December 2019. The new coronavirus (2019 novel coronavirus (2019-nCoV)) can cause multiple organ damage, mainly to lung tissue, and induce inflammation in the body. OBJECTIVES: To investigate the changes of high-density lipoprotein (HDL) level in patients with COVID-19 and assess its value in the evaluation and prognosis of this disease. MATERIAL AND METHODS: This paper is a cross-sectional retrospective study. Eighty-six severe COVID-19 patients, 132 non-severe COVID-19 patients and 76 healthy individuals (control group) were recruited to measure triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) using enzyme-coupled colorimetry. RESULTS: The serum HDL-C level in COVID-19 group was 1.02 +/-0.28 mmol/L which was significantly lower than in control group (1.52 +/-0.55 mmol/L) (p < 0.05). In addition, the serum HDL-C level in severe COVID-19 group was 0.83 +/-1.67 mmol/L, which was significantly lower than that in non-severe COVID-19 group (1.15 +/-0.27 mmol/L) (p < 0.05). CONCLUSIONS: Changes in HDL levels in patients with COVID-19 can reflect the severity of the disease and have a clinical significance in establishing the prognosis.
Adv+Clin+Exp+Med 2021 ; 30 (2): 153-156
