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10.1590/2175-8239-JBN-2020-0144

http://scihub22266oqcxt.onion/10.1590/2175-8239-JBN-2020-0144
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suck abstract from ncbi

pmid33570081      J+Bras+Nefrol 2021 ; 43 (3): 349-358
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  • Acute kidney injury in patients with Covid-19 in a Brazilian ICU: incidence, predictors and in-hospital mortality #MMPMID33570081
  • Costa RLD; Soria TC; Salles EF; Gerecht AV; Corvisier MF; Menezes MAM; Avila CDS; Silva ECF; Pereira SRN; Simvoulidis LFN
  • J Bras Nefrol 2021[Jul]; 43 (3): 349-358 PMID33570081show ga
  • INTRODUCTION: There is little data in the literature on acute kidney injury (AKI) in Covid-19 cases, although relevant in clinical practice in the ICU, especially in Brazil. Our goal was to identify the incidence of AKI, predictive factors and impact on hospital mortality. METHOD: Retrospective cohort of patients with Covid-19 admitted to the ICU. AKI was defined according to KDIGO criteria. Data was collected from electronic medical records between March 17 and April 26. RESULTS: Of the 102 patients, 55.9% progressed with AKI, and the majority (66.7%) was classified as stage 3. Multivariate logistic regression showed age (RC 1.101; 95% CI 1.026 - 1.181; p = 0.0070), estimated glomerular filtration rate - eGFR (RC 1.127; 95% CI 1.022 - 1.243; p = 0.0170) and hypertension (RC 3.212; 95% CI 1.065 - 9.690; p = 0.0380) as independent predictors of AKI. Twenty-three patients died. In the group without kidney injury, there were 8.9% deaths, while in the group with AKI, 33.3% of patients died (RR 5.125; 95% CI 1.598 - 16.431; p = 0.0060). The average survival, in days, was higher in the group without AKI. Cox multivariate analysis showed age (RR 1.054; 95% CI 1.014 - 1.095; p = 0.0080) and severe acute respiratory distress syndrome (RR 8.953; 95% CI 1.128 - 71.048; p = 0.0380) as predictors of hospital mortality. CONCLUSION: We found a high incidence of AKI; and as predictive factors for its occurrence: age, eGFR and hypertension. AKI was associated with higher hospital mortality.
  • |*Acute Kidney Injury/epidemiology[MESH]
  • |*COVID-19[MESH]
  • |Brazil/epidemiology[MESH]
  • |Hospital Mortality[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Intensive Care Units[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]


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