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10.1183/16000617.0242-2020

http://scihub22266oqcxt.onion/10.1183/16000617.0242-2020
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33568525!7879496!33568525
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suck abstract from ncbi


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pmid33568525      Eur+Respir+Rev 2021 ; 30 (159): ä
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  • The impact of outdoor air pollution on COVID-19: a review of evidence from in vitro, animal, and human studies #MMPMID33568525
  • Bourdrel T; Annesi-Maesano I; Alahmad B; Maesano CN; Bind MA
  • Eur Respir Rev 2021[Mar]; 30 (159): ä PMID33568525show ga
  • Studies have pointed out that air pollution may be a contributing factor to the coronavirus disease 2019 (COVID-19) pandemic. However, the specific links between air pollution and severe acute respiratory syndrome-coronavirus-2 infection remain unclear. Here we provide evidence from in vitro, animal and human studies from the existing literature. Epidemiological investigations have related various air pollutants to COVID-19 morbidity and mortality at the population level, however, those studies suffer from several limitations. Air pollution may be linked to an increase in COVID-19 severity and lethality through its impact on chronic diseases, such as cardiopulmonary diseases and diabetes. Experimental studies have shown that exposure to air pollution leads to a decreased immune response, thus facilitating viral penetration and replication. Viruses may persist in air through complex interactions with particles and gases depending on: 1) chemical composition; 2) electric charges of particles; and 3) meteorological conditions such as relative humidity, ultraviolet (UV) radiation and temperature. In addition, by reducing UV radiation, air pollutants may promote viral persistence in air and reduce vitamin D synthesis. Further epidemiological studies are needed to better estimate the impact of air pollution on COVID-19. In vitro and in vivo studies are also strongly needed, in particular to more precisely explore the particle-virus interaction in air.
  • |Air Pollutants/adverse effects[MESH]
  • |Air Pollution/*adverse effects[MESH]
  • |Animals[MESH]
  • |COVID-19/*epidemiology/mortality/transmission/*virology[MESH]
  • |Environmental Exposure/*adverse effects[MESH]
  • |Host-Pathogen Interactions[MESH]
  • |Humans[MESH]
  • |Prognosis[MESH]
  • |Risk Assessment[MESH]
  • |Risk Factors[MESH]
  • |SARS-CoV-2/*pathogenicity[MESH]


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