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Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Braz+J+Infect+Dis 2021 ; 25 (1): 101541 Nephropedia Template TP
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Organizing pneumonia: A late phase complication of COVID-19 responding dramatically to corticosteroids #MMPMID33567251
de Oliveira Filho CM; Vieceli T; de Fraga Bassotto C; da Rosa Barbato JP; Garcia TS; Scheffel RS
Braz J Infect Dis 2021[Jan]; 25 (1): 101541 PMID33567251show ga
Organizing pneumonia emerges as a late phase complication of COVID-19. Corticosteroids are standard therapy for organizing pneumonia, but the question of whether an approach with high dose corticosteroids would be beneficial for patients with organizing pneumonia secondary to COVID-19 remains to be answered. Herein we report a series of three patients, one male and two females, mean age 58.3 years old, admitted for COVID-19 with severe pulmonary disease requiring ventilatory support. The patients underwent chest computed tomography scans due to maintained hypoxemia, which showed a pattern compatible with organizing pneumonia. The patients were treated with a high dose of corticosteroids (prednisone 1?mg/kg PO), showing marked clinical improvement, and decreasing oxygen flow ratio demand. They were discharged after a mean period of 6.3 days of hospitalization. Our report suggests that patients with COVID-19 with organizing pneumonia might benefit from high dose corticosteroids as an adjuvant therapy.