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10.1111/imr.12953 http://scihub22266oqcxt.onion/10.1111/imr.12953 33559128!8014162!33559128     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Immunol+Rev 2021 ; 299 (1): 108-117 Nephropedia Template TP {{tp|p=33559128|t=2021. Human antiviral B cell responses: Emerging lessons from hepatitis B and COVID-19 |pdf=|usr=}}{{33559128}} gab.com Text Human antiviral B cell responses: Emerging lessons from hepatitis B and COVID-19 JO: Immunol Rev http://www.kidney.de/pget.php?&tw=1&pmid=33559128 #FOAvip Humoral immunity is a critical component of the coordinated response required to resolve viral infections and mediate protection following pathogen clearance or vaccination. A better understanding of factors shaping the memory B cell response will allow tailored development of efficient preventative vaccines against emerging acute viral infections, therapeutic vaccines, and immunotherapies for chronic viral infections. Here, we use recent data obtained by profiling antigen-specific B cell responses in hepatitis B as a framework to explore lessons that can be learnt from different viral infections about the diverse influences on humoral immunity. Hepatitis B provides a paradigm where successful B cell responses in resolved or vaccinated individuals can be contrasted to the failed response in chronic infection, while also exemplifying the degree to which B cell responses within infected individuals can differ to two antigens from the same virus. Drawing on studies in other human and murine infections, including emerging data from COVID-19, we consider the influence of antigen quantity and structure on the quality of the B cell response, the role of differential CD4 help, the importance of germinal center vs extrafollicular responses and the emerging concept that responses residing in non-lymphoid organs can participate in B cell memory. Twit Text FOAVip Human antiviral B cell responses: Emerging lessons from hepatitis B and COVID-19 ????Immunol Rev http://www.kidney.de/pget.php?&tw=1&pmid=33559128 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33559128 #FOAvip English Wikipedia <ref>{{Cite pmid|33559128}}</ref> Human antiviral B cell responses: Emerging lessons from hepatitis B and COVID-19 #MMPMID33559128 Burton AR; Maini MK Immunol Rev 2021[Jan]; 299 (1): 108-117 PMID33559128show ga Humoral immunity is a critical component of the coordinated response required to resolve viral infections and mediate protection following pathogen clearance or vaccination. A better understanding of factors shaping the memory B cell response will allow tailored development of efficient preventative vaccines against emerging acute viral infections, therapeutic vaccines, and immunotherapies for chronic viral infections. Here, we use recent data obtained by profiling antigen-specific B cell responses in hepatitis B as a framework to explore lessons that can be learnt from different viral infections about the diverse influences on humoral immunity. Hepatitis B provides a paradigm where successful B cell responses in resolved or vaccinated individuals can be contrasted to the failed response in chronic infection, while also exemplifying the degree to which B cell responses within infected individuals can differ to two antigens from the same virus. Drawing on studies in other human and murine infections, including emerging data from COVID-19, we consider the influence of antigen quantity and structure on the quality of the B cell response, the role of differential CD4 help, the importance of germinal center vs extrafollicular responses and the emerging concept that responses residing in non-lymphoid organs can participate in B cell memory. |Antibodies, Viral/*metabolism[MESH] |Antibody Formation[MESH] |Antigens, Viral/immunology[MESH] |B-Lymphocytes/*immunology[MESH] |COVID-19 Vaccines/*immunology[MESH] |COVID-19/*immunology[MESH] |Hepatitis B virus/*physiology[MESH] |Hepatitis B/*immunology[MESH] |Humans[MESH] |Immunity, Humoral[MESH] |Immunodominant Epitopes/immunology[MESH] |Immunologic Memory[MESH] |SARS-CoV-2/*physiology[MESH]Human antiviral B cell responses: Emerging lessons from hepatitis B an(epmc).pdf DeepDyve Pubget Overpricing