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10.1016/j.waojou.2021.100517

http://scihub22266oqcxt.onion/10.1016/j.waojou.2021.100517
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33558825!7857113!33558825
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suck abstract from ncbi


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pmid33558825      World+Allergy+Organ+J 2021 ; 14 (2): 100517
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  • COVID-19 vaccine-associated anaphylaxis: A statement of the World Allergy Organization Anaphylaxis Committee #MMPMID33558825
  • Turner PJ; Ansotegui IJ; Campbell DE; Cardona V; Ebisawa M; El-Gamal Y; Fineman S; Geller M; Gonzalez-Estrada A; Greenberger PA; Leung ASY; Levin ME; Muraro A; Sanchez Borges M; Senna G; Tanno LK; Yu-Hor Thong B; Worm M
  • World Allergy Organ J 2021[Feb]; 14 (2): 100517 PMID33558825show ga
  • Vaccines against COVID-19 (and its emerging variants) are an essential global intervention to control the current pandemic situation. Vaccines often cause adverse events; however, the vast majority of adverse events following immunization (AEFI) are a consequence of the vaccine stimulating a protective immune response, and not allergic in etiology. Anaphylaxis as an AEFI is uncommon, occurring at a rate of less than 1 per million doses for most vaccines. However, within the first days of initiating mass vaccination with the Pfizer-BioNTech COVID-19 vaccine BNT162b2, there were reports of anaphylaxis from the United Kingdom and United States. More recent data imply an incidence of anaphylaxis closer to 1:200,000 doses with respect to the Pfizer-BioNTech vaccine. In this position paper, we discuss the background to reactions to the current COVID-19 vaccines and relevant steps to mitigate against the risk of anaphylaxis as an AEFI. We propose a global surveillance strategy led by allergists in order to understand the potential risk and generate data to inform evidence-based guidance, and thus provide reassurance to public health bodies and members of the public.
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