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10.1038/s41416-021-01275-3

http://scihub22266oqcxt.onion/10.1038/s41416-021-01275-3
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33558708!8039040!33558708
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suck abstract from ncbi


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pmid33558708      Br+J+Cancer 2021 ; 124 (8): 1361-1365
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  • Recovery strategies following COVID-19 disruption to cervical cancer screening and their impact on excess diagnoses #MMPMID33558708
  • Castanon A; Rebolj M; Pesola F; Sasieni P
  • Br J Cancer 2021[Apr]; 124 (8): 1361-1365 PMID33558708show ga
  • BACKGROUND: The COVID-19 pandemic has disrupted cervical cancer screening services. Assuming increases to screening capacity are unrealistic, we propose two recovery strategies: one extends the screening interval by 6 months for all and the other extends the interval by 36/60 months, but only for women who have already missed being screened. METHODS: Using routine statistics from England we estimate the number of women affected by delays to screening. We used published research to estimate the proportion of screening age women with high-grade cervical intraepithelial neoplasia and progression rates to cancer. Under two recovery scenarios, we estimate the impact of COVID-19 on cervical cancer over one screening cycle (3 years at ages 25-49 and 5 years at ages 50-64 years). The duration of disruption in both scenarios is 6 months. In the first scenario, 10.7 million women have their screening interval extended by 6 months. In the second, 1.5 million women (those due to be screened during the disruption) miss one screening cycle, but most women have no delay. RESULTS: Both scenarios result in similar numbers of excess cervical cancers: 630 vs. 632 (both 4.3 per 100,000 women in the population). However, the scenario in which some women miss one screening cycle creates inequalities-they would have much higher rates of excess cancer: 41.5 per 100,000 delayed for screened women compared to those with a 6-month delay (5.9 per 100,000). CONCLUSION: To ensure equity for those affected by COVID-19 related screening delays additional screening capacity will need to be paired with prioritising the screening of overdue women.
  • |*Early Detection of Cancer[MESH]
  • |Adult[MESH]
  • |COVID-19/complications/*diagnosis/epidemiology/virology[MESH]
  • |Colposcopy/methods[MESH]
  • |England/epidemiology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Papillomaviridae/pathogenicity[MESH]
  • |Papillomavirus Infections/complications/*diagnosis/epidemiology/virology[MESH]
  • |Pregnancy[MESH]
  • |SARS-CoV-2/genetics/pathogenicity[MESH]
  • |Uterine Cervical Neoplasms/complications/*diagnosis/epidemiology/virology[MESH]


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