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Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 BMC+Infect+Dis 2021 ; 21 (1): 155 Nephropedia Template TP
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Clinical characteristics of inpatients with coronavirus disease 2019 (COVID-19) in Sichuan province #MMPMID33557777
Wang W; Chen L; He Q; Wang M; Liu M; Deng T; Deng X; Yang J; Jiang O; Li R; Long B; Mai G; Huan W; Li W; Jiang X; Wen Z; Chen Y; Fu W; Long Z; Zeng F; Chen Y; Du Y; Tang J; Sun X; Li W
BMC Infect Dis 2021[Feb]; 21 (1): 155 PMID33557777show ga
BACKGROUND: The outbreak of COVID-19 has resulted in serious concerns in China and abroad. To investigate clinical features of confirmed and suspected patients with COVID-19 in west China, and to examine differences between severe versus non-severe patients. METHODS: Patients admitted for COVID-19 between January 21 and February 11 from fifteen hospitals in Sichuan Province, China were included. Experienced clinicians trained with methods abstracted data from medical records using pre-defined, pilot-tested forms. Clinical characteristics between severe and non-severe patients were compared. RESULTS: Of the 169 patients included, 147 were laboratory-confirmed, 22 were suspected. For confirmed cases, the most common symptoms from onset to admission were cough (70.7%), fever (70.5%) and sputum (33.3%), and the most common chest CT patterns were patchy or stripes shadowing (78.0%); throughout the course of disease, 19.0% had no fever, and 12.4% had no radiologic abnormality; twelve (8.2%) received mechanical ventilation, four (2.7%) were transferred to ICU, and no death occurred. Compared to non-severe cases, severe ones were more likely to have underlying comorbidities (62.5% vs 26.2%, P = 0.001), to present with cough (92.0% vs 66.4%, P = 0.02), sputum (60.0% vs 27.9%, P = 0.004) and shortness of breath (40.0% vs 8.2%, P < 0.0001), and to have more frequent lymphopenia (79.2% vs 43.7%, P = 0.003) and eosinopenia (84.2% vs 57.0%, P = 0.046). CONCLUSIONS: The symptoms of patients in west China were relatively mild, and an appreciable proportion of infected cases had no fever, warranting special attention.