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Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Am+J+Hosp+Palliat+Care 2021 ; 38 (12): 1503-1508 Nephropedia Template TP
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Interim Analysis of Attrition Rates in Palliative Care Study on Dignity Therapy #MMPMID33557587
Samuels V; Schoppee TM; Greenlee A; Gordon D; Jean S; Smith V; Reed T; Kittelson S; Quest T; O'Mahony S; Hauser J; Guay MOD; Rabow MW; Emanuel L; Fitchett G; Handzo G; Chochinov HM; Yao Y; Wilkie DJ
Am J Hosp Palliat Care 2021[Dec]; 38 (12): 1503-1508 PMID33557587show ga
A routine threat to palliative care research is participants not completing studies. The purpose of this analysis was to quantify attrition rates mid-way through a palliative care study on Dignity Therapy and describe the reasons cited for attrition. Enrolled in the study were a total of 365 outpatients with cancer who were receiving outpatient specialty palliative care (mean age 66.7 +/- 7.3 years, 56% female, 72% White, 22% Black, 6% other race/ethnicity). These participants completed an initial screening for cognitive status, performance status, physical distress, and spiritual distress. There were 76 eligible participants who did not complete the study (58% female, mean age 67.9 +/- 7.3 years, 76% White, 17% Black, and 7% other race). Of those not completing the study, the average scores were 74.5 +/- 11.7 on the Palliative Performance Scale and 28.3 +/- 1.5 on the Mini-Mental Status Examination, whereas 22% had high spiritual distress scores and 45% had high physical distress scores. The most common reason for attrition was death/decline of health (47%), followed by patient withdrawal from the study (21%), and patient lost to follow-up (21%). The overall attrition rate was 24% and within the a priori projected attrition rate of 20%-30%. Considering the current historical context, this interim analysis is important because it will serve as baseline data on attrition prior to the outbreak of the COVID-19 pandemic. Future research will compare these results with attrition throughout the rest of the study, allowing analysis of the effect of the COVID-19 pandemic on the study attrition.