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10.1080/21548331.2021.1887677

http://scihub22266oqcxt.onion/10.1080/21548331.2021.1887677
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33554684!7938650!33554684
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suck abstract from ncbi

pmid33554684      Hosp+Pract+(1995) 2021 ; 49 (3): 157-163
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  • SARS-CoV-2 invasion of the central nervous: a brief review #MMPMID33554684
  • Siddiqui R; Mungroo MR; Khan NA
  • Hosp Pract (1995) 2021[Aug]; 49 (3): 157-163 PMID33554684show ga
  • There is increasing evidence of the ability of the novel coronavirus to invade the central nervous system (CNS). But how does a respiratory virus invade the highly protected CNS? Here, we reviewed available literature and case reports to determine CNS involvement in COVID-19, and to identify potential regions of the brain that may be affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its possible route of entry into the brain to identify its pathogenicity. Based on the symptoms, the parietal lobe and the cerebellum are the likely targets of SARS-CoV-2; however, further work is needed to elucidate this. The presence of ACE2, used by SARS-CoV-2 for cell entry, in the brain as well as detection of the virus in the cerebrospinal fluid, further assert that SARS-COV-2 targets the brain, and therefore, medical practitioners should take that into account when dealing with patients suffering from COVID-19.
  • |Blood-Brain Barrier/pathology/*virology[MESH]
  • |Brain/virology[MESH]
  • |COVID-19/pathology/*virology[MESH]
  • |Central Nervous System/pathology/*virology[MESH]
  • |Cerebrospinal Fluid/virology[MESH]
  • |Humans[MESH]


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