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10.1016/j.virol.2021.01.002 http://scihub22266oqcxt.onion/10.1016/j.virol.2021.01.002 33550117!7831474!33550117     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33550117&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Virology 2021 ; 556 (?): 79-86 Nephropedia Template TP {{tp|p=33550117|t=2021. A novel ratio of CD8(+):B-cells as a prognostic marker of coronavirus disease 2019 patient progression and outcome |pdf=|usr=}}{{33550117}} gab.com Text A novel ratio of CD8(+):B-cells as a prognostic marker of coronavirus disease 2019 patient progression and outcome JO: Virology http://www.kidney.de/pget.php?&tw=1&pmid=33550117 #FOAvip Infection with SARS-COV-2 may result in severe pneumonia potentially leading to mechanical ventilation and intensive care treatment. The aim of the present study was to analyze the immune responses in critically ill coronavirus 2019 (COVID-19) patients requiring mechanical ventilation and assess their potential use as markers of clinical progression and outcome. Confirmed COVID-19 patients were grouped into those requiring mechanical ventilation (intubated) and non-intubated. Immune phenotyping was performed and cytokine levels were determined. A novel ratio of CD8(+):B cells was significantly lower in intubated versus non-intubated (p = 0.015) and intubated non-survivors (NSV) versus survivors (SV) (p = 0.015). The same ratio correlated with outcome, CRP, IL-6 levels and neutrophil count. Receiving operating curve (ROC) analysis for prediction of requirement of mechanical ventilation by the CD8(+):B cells ratio revealed an AUC of 0.747 and a p = 0.007. The ratio of CD8(+):B cells may serve as a useful prognostic marker for disease severity and outcome. Twit Text FOAVip A novel ratio of CD8(+):B-cells as a prognostic marker of coronavirus disease 2019 patient progression and outcome ????Virology http://www.kidney.de/pget.php?&tw=1&pmid=33550117 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33550117 #FOAvip English Wikipedia <ref>{{Cite pmid|33550117}}</ref> A novel ratio of CD8(+):B-cells as a prognostic marker of coronavirus disease 2019 patient progression and outcome #MMPMID33550117 Detsika MG; Ampelakiotou K; Grigoriou E; Psarra K; Jahaj E; Roussos C; Dimopoulou I; Orfanos SE; Tsirogianni A; Kotanidou A Virology 2021[Apr]; 556 (?): 79-86 PMID33550117show ga Infection with SARS-COV-2 may result in severe pneumonia potentially leading to mechanical ventilation and intensive care treatment. The aim of the present study was to analyze the immune responses in critically ill coronavirus 2019 (COVID-19) patients requiring mechanical ventilation and assess their potential use as markers of clinical progression and outcome. Confirmed COVID-19 patients were grouped into those requiring mechanical ventilation (intubated) and non-intubated. Immune phenotyping was performed and cytokine levels were determined. A novel ratio of CD8(+):B cells was significantly lower in intubated versus non-intubated (p = 0.015) and intubated non-survivors (NSV) versus survivors (SV) (p = 0.015). The same ratio correlated with outcome, CRP, IL-6 levels and neutrophil count. Receiving operating curve (ROC) analysis for prediction of requirement of mechanical ventilation by the CD8(+):B cells ratio revealed an AUC of 0.747 and a p = 0.007. The ratio of CD8(+):B cells may serve as a useful prognostic marker for disease severity and outcome. |Aged[MESH] |B-Lymphocytes/*pathology[MESH] |Biomarkers/blood[MESH] |CD8-Positive T-Lymphocytes/*pathology[MESH] |COVID-19/*immunology/pathology/therapy[MESH] |Critical Illness[MESH] |Cytokines/blood[MESH] |Female[MESH] |Humans[MESH] |Immunophenotyping[MESH] |Lymphocyte Count[MESH] |Male[MESH] |Middle Aged[MESH] |Prognosis[MESH] |Respiration, Artificial[MESH] |SARS-CoV-2[MESH]A novel ratio of CD8(+):B-cells as a prognostic marker of coronavirus (epmc).pdf DeepDyve Pubget Overpricing