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10.1016/j.jamda.2021.01.070

http://scihub22266oqcxt.onion/10.1016/j.jamda.2021.01.070
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suck abstract from ncbi


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pmid33549565      J+Am+Med+Dir+Assoc 2021 ; 22 (3): 498-503
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  • Signs, Symptoms, and Comorbidities Associated With Onset and Prognosis of COVID-19 in a Nursing Home #MMPMID33549565
  • Tobolowsky FA; Bardossy AC; Currie DW; Schwartz NG; Zacks RLT; Chow EJ; Dyal JW; Ali H; Kay M; Duchin JS; Brostrom-Smith C; Clark S; Sykes K; Jernigan JA; Honein MA; Clark TA; Stone ND; Reddy SC; Rao AK
  • J Am Med Dir Assoc 2021[Mar]; 22 (3): 498-503 PMID33549565show ga
  • BACKGROUND: Effective halting of outbreaks in skilled nursing facilities (SNFs) depends on the earliest recognition of cases. We assessed confirmed COVID-19 cases at an SNF impacted by COVID-19 in the United States to identify early indications of COVID-19 infection. METHODS: We performed retrospective reviews of electronic health records for residents with laboratory-confirmed SARS-CoV-2 during February 28-March 16, 2020. Records were abstracted for comorbidities, signs and symptoms, and illness outcomes during the 2 weeks before and after the date of positive specimen collection. Relative risks (RRs) of hospitalization and death were calculated. RESULTS: Of the 118 residents tested among approximately 130 residents from Facility A during February 28-March 16, 2020, 101 (86%) were found to test positive for SARS-CoV-2. At initial presentation, about two-thirds of SARS-CoV-2-positive residents had an abnormal vital sign or change in oxygen status. Most (90.2%) symptomatic residents had elevated temperature, change in mental status, lethargy, change in oxygen status, or cough; 9 (11.0%) did not have fever, cough, or shortness of breath during their clinical course. Those with change in oxygen status had an increased relative risk (RR) of 30-day mortality [51.1% vs 29.7%, RR 1.7, 95% confidence interval (CI) 1.0-3.0]. RR of hospitalization was higher for residents with underlying hepatic disease (1.6, 95% CI 1.1-2.2) or obesity (1.5, 95% CI 1.1-2.1); RR of death was not statistically significant. CONCLUSIONS AND IMPLICATIONS: Our findings reinforce the critical role that monitoring of signs and symptoms can have in identifying COVID-19 cases early. SNFs should ensure they have a systematic approach for responding to abnormal vital signs and oxygen saturation and consider ensuring common signs and symptoms identified in Facility A are among those they monitor.
  • |*Skilled Nursing Facilities[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19 Testing/methods[MESH]
  • |COVID-19/*diagnosis/physiopathology[MESH]
  • |Comorbidity[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Medical Records[MESH]
  • |Middle Aged[MESH]
  • |Prognosis[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2/isolation & purification[MESH]


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