Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.celrep.2021.108737 http://scihub22266oqcxt.onion/10.1016/j.celrep.2021.108737 33545052!7835103!33545052     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Rep 2021 ; 34 (7): 108737 Nephropedia Template TP {{tp|p=33545052|t=2021. Cross-reactivity of SARS-CoV structural protein antibodies against SARS-CoV-2 |pdf=|usr=}}{{33545052}} gab.com Text Cross-reactivity of SARS-CoV structural protein antibodies against SARS-CoV-2 JO: Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=33545052 #FOAvip In the ongoing coronavirus disease 2019 (COVID-19) pandemic, there remain unanswered questions regarding the nature and significance of the humoral immune response toward other coronavirus infections. Here, we investigate the cross-reactivity of antibodies raised against the first severe acute respiratory syndrome coronavirus (SARS-CoV) for their reactivity toward SARS-CoV-2. We extensively characterize a selection of 10 antibodies covering all of the SARS-CoV structural proteins: spike, membrane, nucleocapsid, and envelope. Although nearly all of the examined SARS-CoV antibodies display some level of reactivity to SARS-CoV-2, we find only partial cross-neutralization for the spike antibodies. The implications of our work are two-fold. First, we establish a set of antibodies with known reactivity to both SARS-CoV and SARS-CoV-2, which will allow further study of both viruses. Second, we provide empirical evidence of the high propensity for antibody cross-reactivity between distinct strains of human coronaviruses, which is critical information for designing diagnostic and vaccine strategies for COVID-19. Twit Text FOAVip Cross-reactivity of SARS-CoV structural protein antibodies against SARS-CoV-2 ????Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=33545052 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33545052 #FOAvip English Wikipedia <ref>{{Cite pmid|33545052}}</ref> Cross-reactivity of SARS-CoV structural protein antibodies against SARS-CoV-2 #MMPMID33545052 Bates TA; Weinstein JB; Farley S; Leier HC; Messer WB; Tafesse FG Cell Rep 2021[Feb]; 34 (7): 108737 PMID33545052show ga In the ongoing coronavirus disease 2019 (COVID-19) pandemic, there remain unanswered questions regarding the nature and significance of the humoral immune response toward other coronavirus infections. Here, we investigate the cross-reactivity of antibodies raised against the first severe acute respiratory syndrome coronavirus (SARS-CoV) for their reactivity toward SARS-CoV-2. We extensively characterize a selection of 10 antibodies covering all of the SARS-CoV structural proteins: spike, membrane, nucleocapsid, and envelope. Although nearly all of the examined SARS-CoV antibodies display some level of reactivity to SARS-CoV-2, we find only partial cross-neutralization for the spike antibodies. The implications of our work are two-fold. First, we establish a set of antibodies with known reactivity to both SARS-CoV and SARS-CoV-2, which will allow further study of both viruses. Second, we provide empirical evidence of the high propensity for antibody cross-reactivity between distinct strains of human coronaviruses, which is critical information for designing diagnostic and vaccine strategies for COVID-19. |Antibodies, Viral/*immunology[MESH] |COVID-19/immunology/virology[MESH] |Coronavirus Infections/immunology/virology[MESH] |Cross Reactions/immunology[MESH] |HEK293 Cells[MESH] |Humans[MESH] |Immunity, Humoral/immunology[MESH] |Pandemics[MESH] |SARS-CoV-2/genetics/*immunology[MESH] |Severe acute respiratory syndrome-related coronavirus/genetics/*immunology[MESH]Cross-reactivity of SARS-CoV structural protein antibodies against SAR(epmc).pdf DeepDyve Pubget Overpricing