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10.1136/bcr-2020-241105 http://scihub22266oqcxt.onion/10.1136/bcr-2020-241105 33541971!7868223!33541971     free     free     free       BMJ+Case+Rep 2021 ; 14 (2): ä Nephropedia Template TP {{tp|p=33541971|t=2021. Steroid harms if given early in COVID-19 viraemia |pdf=|usr=}}{{33541971}} gab.com Text Steroid harms if given early in COVID-19 viraemia JO: BMJ Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=33541971 #FOAvip COVID-19 is a biphasic illness with an initial viraemia phase and later effective adaptive immune phase, except in a minority of people who develop severe disease. Immune regulation is the key target to treat COVID illness. In anticipation, an elderly man self-medicated himself with dexamethasone on the day of symptom onset of a flu-like illness, took other symptomatic measures and was tested positive for SARS-CoV-2. His condition deteriorated with each passing day resulting in hospitalisation. He demanded oxygen and declared as severe COVID. With supportive treatment, he recovered after the 20th day of illness. Immunosuppression and anti-inflammation are likely to benefit when the immune response is dysregulated and turning into a cytokine storm. A medication that has saved many could be the one predisposing to severity if taken as a preventive measure, too early in the disease course, especially the viraemia phase. Twit Text FOAVip Steroid harms if given early in COVID-19 viraemia ????BMJ Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=33541971 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33541971 #FOAvip English Wikipedia <ref>{{Cite pmid|33541971}}</ref> Steroid harms if given early in COVID-19 viraemia #MMPMID33541971 Arora K; Panda PK BMJ Case Rep 2021[Feb]; 14 (2): ä PMID33541971show ga COVID-19 is a biphasic illness with an initial viraemia phase and later effective adaptive immune phase, except in a minority of people who develop severe disease. Immune regulation is the key target to treat COVID illness. In anticipation, an elderly man self-medicated himself with dexamethasone on the day of symptom onset of a flu-like illness, took other symptomatic measures and was tested positive for SARS-CoV-2. His condition deteriorated with each passing day resulting in hospitalisation. He demanded oxygen and declared as severe COVID. With supportive treatment, he recovered after the 20th day of illness. Immunosuppression and anti-inflammation are likely to benefit when the immune response is dysregulated and turning into a cytokine storm. A medication that has saved many could be the one predisposing to severity if taken as a preventive measure, too early in the disease course, especially the viraemia phase. |*COVID-19 Drug Treatment[MESH] |Aged[MESH] |Anti-Infective Agents/therapeutic use[MESH] |Anti-Inflammatory Agents/*adverse effects/therapeutic use[MESH] |COVID-19/complications[MESH] |Dexamethasone/*adverse effects/therapeutic use[MESH] |Hospitalization[MESH] |Humans[MESH] |Hydroxychloroquine/therapeutic use[MESH] |Male[MESH] |Pneumonia, Viral/complications/drug therapy[MESH] |SARS-CoV-2/isolation & purification[MESH] |Self Medication/methods[MESH] |Steroids/adverse effects/therapeutic use[MESH] |Treatment Outcome[MESH]Steroid harms if given early in COVID-19 viraemia (epmc).pdf DeepDyve Pubget Overpricing