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10.1136/bcr-2020-240243

http://scihub22266oqcxt.onion/10.1136/bcr-2020-240243
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33541953!7868273!33541953
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suck abstract from ncbi


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pmid33541953      BMJ+Case+Rep 2021 ; 14 (2): ä
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  • Hypereosinophilic syndrome with multiorgan involvement: an interdisciplinary work-up #MMPMID33541953
  • Looman KIM; Nuver ME; Korevaar TIM; Guillen SS
  • BMJ Case Rep 2021[Feb]; 14 (2): ä PMID33541953show ga
  • A previously healthy 40-year-old man was referred to our emergency department with pruritic skin lesions and dyspnoea. Laboratory investigation revealed hypereosinophilia. Further diagnostic work-up confirmed the diagnosis of idiopathic hypereosinophilic syndrome (iHES), a rare myeloproliferative disease with a heterogeneous clinical presentation. We describe a unique case with cardiac, pulmonary, hepatic and cutaneous involvement at time of presentation. This case accentuates the importance of an extensive multidisciplinary diagnostic work-up, since iHES is a condition with potential rapid progressive multiorgan failure which requires prompt analysis and treatment. In addition, this case emphasises the importance of being aware of tunnel vision, especially during the COVID-19 pandemic, which might give rise to an increased risk of missing rare diagnoses. Our patient was treated with prednisolone, after which both his clinical condition and eosinophil concentrations markedly improved.
  • |Adult[MESH]
  • |Anti-Inflammatory Agents/therapeutic use[MESH]
  • |Biopsy/methods[MESH]
  • |COVID-19/diagnosis[MESH]
  • |Diagnosis, Differential[MESH]
  • |Dyspnea/complications[MESH]
  • |Eosinophils/pathology[MESH]
  • |Humans[MESH]
  • |Hypereosinophilic Syndrome/complications/*diagnosis/drug therapy/*pathology[MESH]
  • |Male[MESH]
  • |Prednisolone/therapeutic use[MESH]
  • |SARS-CoV-2[MESH]
  • |Skin Diseases/complications/diagnosis[MESH]
  • |Tomography, X-Ray Computed/methods[MESH]


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