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10.3390/cells10020302 http://scihub22266oqcxt.onion/10.3390/cells10020302 33540625!7912962!33540625     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cells 2021 ; 10 (2): ä Nephropedia Template TP {{tp|p=33540625|t=2021. Thymoquinone: A Tie-Breaker in SARS-CoV2-Infected Cancer Patients?|pdf=|usr=}}{{33540625}} gab.com Text Thymoquinone: A Tie-Breaker in SARS-CoV2-Infected Cancer Patients JO: Cells http://www.kidney.de/pget.php?&tw=1&pmid=33540625 #FOAvip Since the beginning of the SARS-CoV-2(severe acute respiratory syndrome-coronavirus-2) pandemic, arace to develop a vaccine has been initiated, considering the massive and rather significant economic and healthcare hits that this virus has caused. The pathophysiology occurring following COVID-19(coronavirus disease-2019) infection has givenhints regarding the supportive and symptomatic treatments to establish for patients, as no specific anti-SARS-CoV-2 is available yet. Patient symptoms vary greatly and range from mild symptoms to severe fatal complications. Supportive treatments include antipyretics, antiviral therapies, different combinations of broad-spectrum antibiotics, hydroxychloroquine and plasma transfusion. Unfortunately, cancer patients are at higher risk of viral infection and more likely to develop serious complications due to their immunocompromised state, the fact that they are already administering multiple medications, as well as combined comorbidity compared to the general population. It may seem impossible to find a drug that possesses both potent antiviral and anticancer effects specifically against COVID-19 infection and its complications and the existing malignancy, respectively. Thymoquinone (TQ) is the most pharmacologically active ingredient in Nigella sativa seeds (black seeds); it is reported to have anticancer, anti-inflammatory and antioxidant effects in various settings. In this review, we will discuss the multiple effects of TQ specifically against COVID-19, its beneficial effects against COVID-19 pathophysiology and multiple-organ complications, its use as an adjuvant for supportive COVID-19 therapy and cancer therapy, and finally, its anticancer effects. Twit Text FOAVip Thymoquinone: A Tie-Breaker in SARS-CoV2-Infected Cancer Patients ????Cells http://www.kidney.de/pget.php?&tw=1&pmid=33540625 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33540625 #FOAvip English Wikipedia <ref>{{Cite pmid|33540625}}</ref> Thymoquinone: A Tie-Breaker in SARS-CoV2-Infected Cancer Patients? #MMPMID33540625 Elgohary S; Elkhodiry AA; Amin NS; Stein U; El Tayebi HM Cells 2021[Feb]; 10 (2): ä PMID33540625show ga Since the beginning of the SARS-CoV-2(severe acute respiratory syndrome-coronavirus-2) pandemic, arace to develop a vaccine has been initiated, considering the massive and rather significant economic and healthcare hits that this virus has caused. The pathophysiology occurring following COVID-19(coronavirus disease-2019) infection has givenhints regarding the supportive and symptomatic treatments to establish for patients, as no specific anti-SARS-CoV-2 is available yet. Patient symptoms vary greatly and range from mild symptoms to severe fatal complications. Supportive treatments include antipyretics, antiviral therapies, different combinations of broad-spectrum antibiotics, hydroxychloroquine and plasma transfusion. Unfortunately, cancer patients are at higher risk of viral infection and more likely to develop serious complications due to their immunocompromised state, the fact that they are already administering multiple medications, as well as combined comorbidity compared to the general population. It may seem impossible to find a drug that possesses both potent antiviral and anticancer effects specifically against COVID-19 infection and its complications and the existing malignancy, respectively. Thymoquinone (TQ) is the most pharmacologically active ingredient in Nigella sativa seeds (black seeds); it is reported to have anticancer, anti-inflammatory and antioxidant effects in various settings. In this review, we will discuss the multiple effects of TQ specifically against COVID-19, its beneficial effects against COVID-19 pathophysiology and multiple-organ complications, its use as an adjuvant for supportive COVID-19 therapy and cancer therapy, and finally, its anticancer effects. |*Antineoplastic Agents/pharmacology/therapeutic use[MESH] |*Antiviral Agents/pharmacology/therapeutic use[MESH] |*Benzoquinones/pharmacology/therapeutic use[MESH] |*COVID-19 Drug Treatment[MESH] |*COVID-19/complications[MESH] |*Drug Repositioning[MESH] |*Neoplasms/complications/drug therapy[MESH] |Animals[MESH] |Cell Line, Tumor[MESH] |Endoplasmic Reticulum Chaperone BiP[MESH] |Humans[MESH] |Mice[MESH]Thymoquinone: A Tie-Breaker in SARS-CoV2-Infected Cancer Patients?(epmc).pdf DeepDyve Pubget Overpricing